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LONDON, Aug. 11 (Xinhua) -- For young people at high risk of developing schizophrenia, a 12-week intervention1 with omega-3 supplements might reduce the long-term risk of progression to the psychotic disorder2, according to a paper published Tuesday in the journal Nature Communications.
Researchers from Australia and Austria carried out research over nearly seven years on the effect of omega-3 on the risk of psychotic disorder.
Schizophrenia typically manifests in adolescence3 or early adulthood4 and the majority of those affected5 gradually develop a variety of clinically significant signs and symptoms. Diagnostic criteria6, termed "ultra-high risk" criteria have been developed to identify young people more likely to develop psychosis.
Omega-3 supplements may reduce psychosis risk: researchers
Previous studies have implicated7 a lack of omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) in the development of a number of mental health conditions and several trials have shown that supplementation with omega-3 PUFAs can reduce psychotic symptoms.
In 2010, researchers reported that dietary supplements of omega-3 PUFAs, in participants aged8 13 to 25, prevented a first episode of a psychotic disorder for up to one year.
The new report showed that this intervention had long-term effects even after a period of 6.7 years for 71 of the original 81 participants. They found that 9.8 percent of the omega-3 group (4 out 41) developed psychosis compared to 40 percent (16 out of 40) in the placebo9 group. In addition, the placebo group showed more rapid onset10 of psychosis and a higher overall incidence of other psychiatric disorders11.
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1 intervention | |
n.介入,干涉,干预 | |
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2 disorder | |
n.紊乱,混乱;骚动,骚乱;疾病,失调 | |
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3 adolescence | |
n.青春期,青少年 | |
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4 adulthood | |
n.成年,成人期 | |
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5 affected | |
adj.不自然的,假装的 | |
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6 criteria | |
n.标准 | |
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7 implicated | |
adj.密切关联的;牵涉其中的 | |
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8 aged | |
adj.年老的,陈年的 | |
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9 placebo | |
n.安慰剂;宽慰话 | |
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10 onset | |
n.进攻,袭击,开始,突然开始 | |
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11 disorders | |
n.混乱( disorder的名词复数 );凌乱;骚乱;(身心、机能)失调 | |
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12 mechanism | |
n.机械装置;机构,结构 | |
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