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(单词翻译:双击或拖选)
Early signs a new U.S. COVID surge could be on its way
As the U.S. heads into a third pandemic winter, the first hints are emerging that another possible surge of COVID-19 infections could be on its way.
So far, no national surge has started yet. The number of people getting infected, hospitalized and dying from COVID in the U.S. has been gently declining from a fairly high plateau.
But as the weather cools and people start spending more time inside, where the virus spreads more easily, the risks of a resurgence2 increase.
The first hint of what could be in store is what's happening in Europe. Infections have been rising in many European countries, including the U.K., France, and Italy.
"In the past, what's happened in Europe often has been a harbinger for what's about to happen in the United States," says Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota. "So I think the bottom line message for us in this country is: We have to be prepared for what they are beginning to see in Europe."
Several computer models are projecting that COVID infections will continue to recede3 at least through the end of the year. But researchers stress there are many uncertainties4 that could change that, such as whether more infectious variants6 start to spread fast in the U.S.
In fact, scientists are watching a menagerie of new omicron subvariants that have emerged recently that appear to be even better at dodging7 immunity8.
"We look around the world and see countries such as Germany and France are seeing increases as we speak," says Lauren Ancel Meyers, director of the UT COVID-19 Modeling Consortium at the University of Texas at Austin. "That gives me pause. It adds uncertainty9 about what we can expect in the coming weeks and the coming months."
However, it's not certain the U.S. experience will echo Europe's, says Justin Lessler, an epidemiologist at the University of North Carolina who helps run the COVID-19 Scenario10 Modeling Hub.
That's because it's not clear whether Europe's rising cases are related to people's greater susceptibility to new subvariants they've not yet been exposed to. In addition, different countries have different levels of immunity.
"If it is mostly just behavioral changes and climate, we might be able to avoid similar upticks if there is broad uptake of the bivalent vaccine," Lessler says. "If it is immune escape across several variants with convergent11 evolution, the outlook for the U.S. may be more concerning."
In fact, some researchers say the U.S. is already starting to see early signs of that. For example, the levels of virus being detected in wastewater are up in some parts of the country, such in Pennsylvania, Connecticut, Vermont and other parts of the Northeast. That could an early-warning sign of what's coming, though overall the virus is declining nationally.
"It's really too early to say something big is happening, but it's something that we're keeping an eye on," says Amy Kirby, national wastewater surveillance program lead at the Centers for Disease Control and Prevention.
But infections and even hospitalizations have started rising in some of the same parts of New England, as well as some other northern areas, such as the Pacific Northwest, according to Dr. David Rubin, the director of the PolicyLab at Children's Hospital of Philadelphia, which tracks the pandemic.
"We're seeing the northern rim12 of the country beginning to show some evidence of increasing transmission," Rubin says. "The winter resurgence is beginning."
Assuming no dramatically different new variant5 emerges, it appears highly unlikely this year's surge would get as severe as the last two years in terms of severe disease and deaths.
"We have a lot more immunity in the population than we did last winter," says Jennifer Nuzzo, who runs the Pandemic Center at the Brown University School of Public Health.
"Not only have people gotten vaccinated13, but a lot of people have now gotten this virus. In fact, some people have gotten it multiple times. And that does build up [immunity] in the population and reduce overall our risk of severe illness," Nuzzo says.
Another crucial variable that could affect how the impact of a rise of infections is how many people get one of the new bivalent omicron boosters to shore up their waning14 immunity.
But booster uptake in the U.S. was already sluggish15. "Nearly 50% of people who are eligible16 for a booster have not gotten one," says William Hanage, an associate professor of epidemiology at the Harvard T.H. Chan School of Public Health. "It's wild. It's really crazy."
And the demand for the newest boosters is pretty lethargic17 so far. Fewer than 8 million people have gotten one of the new boosters since they became available over the Labor18 Day weekend, even though more than 200 million are eligible.
Given the likelihood of a surge, it's critical that people be up to date on vaccines19, says Nuzzo. "The most important thing that we could do is to take off the table that this virus can cause severe illness and death," she says.
"There are a lot of people who could really benefit from getting boosted but have not done so."
1 transcript | |
n.抄本,誊本,副本,肄业证书 | |
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2 resurgence | |
n.再起,复活,再现 | |
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3 recede | |
vi.退(去),渐渐远去;向后倾斜,缩进 | |
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4 uncertainties | |
无把握( uncertainty的名词复数 ); 不确定; 变化不定; 无把握、不确定的事物 | |
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5 variant | |
adj.不同的,变异的;n.变体,异体 | |
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6 variants | |
n.变体( variant的名词复数 );变种;变型;(词等的)变体 | |
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7 dodging | |
n.避开,闪过,音调改变v.闪躲( dodge的现在分词 );回避 | |
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8 immunity | |
n.优惠;免除;豁免,豁免权 | |
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9 uncertainty | |
n.易变,靠不住,不确知,不确定的事物 | |
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10 scenario | |
n.剧本,脚本;概要 | |
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11 convergent | |
adj.会聚的 | |
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12 rim | |
n.(圆物的)边,轮缘;边界 | |
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13 vaccinated | |
[医]已接种的,种痘的,接种过疫菌的 | |
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14 waning | |
adj.(月亮)渐亏的,逐渐减弱或变小的n.月亏v.衰落( wane的现在分词 );(月)亏;变小;变暗淡 | |
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15 sluggish | |
adj.懒惰的,迟钝的,无精打采的 | |
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16 eligible | |
adj.有条件被选中的;(尤指婚姻等)合适(意)的 | |
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17 lethargic | |
adj.昏睡的,懒洋洋的 | |
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18 labor | |
n.劳动,努力,工作,劳工;分娩;vi.劳动,努力,苦干;vt.详细分析;麻烦 | |
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19 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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