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(单词翻译:双击或拖选)
The Royal Plague It’s good to be king, as the saying goes. But sometimes having a royal lineage isn’t so great. Take the male descendants of Queen Victoria, who was the reigning1 monarch2 of the United Kingdom during most of the 19th century. Victoria’s son, Leopold, died is his thirties when he slipped, fell, and bled to death. Her grandson, Friedrich, met his end at age two, also bleeding to death. Grandsons Leopold and Maurice made it to ages 32 and 23, respectively, before they too, bled out. Now, given all the bleeding, you might assume that Victoria’s male line suffered from hemophilia. And you’d be right. But it wasn’t until 2009 that scientists confirmed that what had been known as “Royal disease” was, in fact hemophilia–a genetic4 mutation5 that disables the ability of blood to clot6. Absent clotting7, even a trivial cut or scratch can turn deadly if too much blood is lost. So how did scientists confirm that it was hemophilia that plagued the royals? By analyzing8 the DNA9 of Victoria’s great grandson, Prince Alexei Romanov. He was murdered along with his entire family during the onset10 of the Russian Revolution in 1918. Using bone fragments, the scientists identified genetic markers for hemophilia B. Prince Alexei shared the same troublesome DNA as other male members of Queen Victoria’s exclusive gene3 pool. So the finding confirmed that all the royals who bled to death did so because of hemophilia. Today, clotting factors and other medications can effectively control hemophilia. But during the 19th century, when no remedy was available, bleeding without end usually meant that you’d reached the end–royalty or not.
1 reigning | |
adj.统治的,起支配作用的 | |
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2 monarch | |
n.帝王,君主,最高统治者 | |
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3 gene | |
n.遗传因子,基因 | |
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4 genetic | |
adj.遗传的,遗传学的 | |
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5 mutation | |
n.变化,变异,转变 | |
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6 clot | |
n.凝块;v.使凝成块 | |
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7 clotting | |
v.凝固( clot的现在分词 );烧结 | |
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8 analyzing | |
v.分析;分析( analyze的现在分词 );分解;解释;对…进行心理分析n.分析 | |
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9 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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10 onset | |
n.进攻,袭击,开始,突然开始 | |
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