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Making Stem Cells From Ordinary Adult Cells Most cells in our bodies are unipotent, that is they stay the same throughout their lives. For example, once a skin cell, always a skin cell–they never start turning into brain cells. The exception is stem cells. As a fertilized1 egg starts to divide and grow into a complete organism, the cells in this developing ball of embryo2 are known as pluripotent stem cells. As these cells divide, they change, or “differentiate,” into muscle, lung, or any other kind of cell needed to build a body. This amazing trait is what makes embryonic3 stem cell research so important. For example, pluripotent stem cells might potentially be used to make new treatments or cures by replacing diseased cells with new ones grown from stem cells. But despite their potential for good, embryonic stem cell research has sparked intense political controversy4. But in 2007, scientists made a revolutionary breakthrough. Three different groups simultaneously5 announced that they had converted unipotent, mature skin cells back into an undifferentiated state. In other words, they had created cells that behaved like embryonic stem cells without using any embryo derived6 materials. These new cells, dubbed7 “induced pluripotent stem cells” or IPS’s could then be converted into a variety of different cell types, such as pancreas, muscle or brain cells. The IPS’s were created by inserting certain genes8 into the DNA9 of the adult cells. The inserted genes turn on cellular10 signals that allow the cell to change into new cell types. This breakthrough brings us closer to exciting possibilities such as custom designed treatments, drugs or tissue transplant using stem cells made from the patient’s own cells.
1 Fertilized | |
v.施肥( fertilize的过去式和过去分词 ) | |
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2 embryo | |
n.胚胎,萌芽的事物 | |
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3 embryonic | |
adj.胚胎的 | |
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4 controversy | |
n.争论,辩论,争吵 | |
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5 simultaneously | |
adv.同时发生地,同时进行地 | |
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6 derived | |
vi.起源;由来;衍生;导出v.得到( derive的过去式和过去分词 );(从…中)得到获得;源于;(从…中)提取 | |
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7 dubbed | |
v.给…起绰号( dub的过去式和过去分词 );把…称为;配音;复制 | |
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8 genes | |
n.基因( gene的名词复数 ) | |
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9 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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10 cellular | |
adj.移动的;细胞的,由细胞组成的 | |
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