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美国国家公共电台 NPR Kevin Jones: Can Embracing Uncertainty Lead To Better Medicine?

时间:2017-02-27 01:55来源:互联网 提供网友:nan   字体: [ ]
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GUY RAZ, HOST:

On the show today, the Spirit of Inquiry1, why the question is often more important than the answer and what happens when one question leads to another?

KEVIN JONES: That's how every medical interview that I have with a patient begins - questions that they have, questions I have for them, trying to put the pieces together and understand what's happening.

RAZ: This is Kevin Jones. He's a surgeon who specializes in a rare group of cancers called sarcomas. And he says doctors, no matter how many questions they ask, definitely don't have all the answers.

JONES: I mean, there's been a fairly paternalistic view of medicine where we just kind of - we take care of patients, you know. We manage all this uncertainty2 and things for them. And I just - I react unhappily to that because I think that there is an element of - certainly not malintent, but there's an element of dishonesty when we presume to know more than we know.

RAZ: I mean, somebody in your position is sought out to give answers, right? Like patients come to you, they say Dr. Jones, you know, am I going to die? And you don't always have the answers.

JONES: Absolutely. No, I mean, we - especially when it comes down to predictions, I mean, just like the weathermen, we're terrible at making predictions. And yet we have to.

RAZ: Here's Kevin Jones on the TED3 stage.

(SOUNDBITE OF TED TALK)

JONES: Medicine is science. Medicine is knowledge in process. Sometimes in the media and even more rarely, but sometimes even scientists will say that something or other has been scientifically proven. But I hope that you understand that science never proves anything definitively4 forever. Now, I am a surgeon, and I would tell you that every one of my patients is an outlier is an exception. People talk about thinking outside the box, but we don't even have a box in sarcoma. What we do have is we take a bath in the uncertainty and unknowns and exceptions and outliers that surround us in sarcoma is easy access to what I think are those two most important values for any science - humility5 and curiosity.

Because if I am humble6 and curious when a patient asks me a question and I don't know the answer, I'll ask a colleague who may have a similar albeit7 distinct patient with sarcoma. We'll even establish international collaborations. Those patients will start to talk to each other through chat rooms and support groups. It's through this kind of humbly8 curious communication that we begin to try and learn new things. Hopefully, science remains9 curious enough to look for and humble enough to recognize when we have found the next outlier, the next exception which teaches us what we don't actually know.

A colleague of mine removed a tumor10 from a patient's limb. He was concerned about this tumor, but his conversations with the patient were exactly what a patient might want. He said I got it all, and you're good to go. She and her husband were thrilled. They went out celebrated11, fancy dinner, opened a bottle of champagne12. The only problem was a few weeks later, she started to notice another nodule in the same area. Turned out, he hadn't gotten it all, and she wasn't good to go.

My colleague came to me and said, Kevin, would you mind looking after this patient for me? I said why? You know the right thing to do as well as I do. You haven't done anything wrong. He said please just look after this patient for me. He was embarrassed, not by what he had done, but by the conversation that he had had, by the overconfidence. So I performed a much more invasive surgery and had a very different conversation with the patient afterwards. I said most likely I've gotten it all, and you're most likely good to go. But this is the experiment that we're doing. We're going to work together to find out if this surgery will work to get rid of your cancer.

(SOUNDBITE OF MUSIC)

RAZ: So basically, you just told her, like, she would always need to be a little uncertain?

JONES: Yeah. We never know completely. We have to be careful about coming across as overly confident. I mean, patients respond very well to physicians who are brimming with confidence. But if it doesn't work - you know, they're taking whatever pill and whatever it was is not getting better - they're kind of banging their head against a wall. And they say, either I did something wrong or my physician's an idiot or (laughter), you know, they start to have incredible distrust of the process.

RAZ: So, I mean, you're saying, like, acknowledge, you know, the room for error - right? - for uncertainty with patients.

JONES: Absolutely, absolutely. You know, you could either have a physician who's a used car salesman or something who says don't pay attention to all these holes that are in our abilities and in our our knowledge. Or you can have a physician that basically functions as a teacher, as a mentor13, in the process of going through this experience and sort of standing14 next to the patient and pointing out the holes (laughter). This is what we don't know. This is what we're yet to find out. And I still think that we can acknowledge, look, I don't have a black-and-white answer for you because it doesn't exist. Anybody who gives you a black-and-white answer is either bluffing15 or is making up some part of it.

(SOUNDBITE OF TED TALK)

JONES: Almost 20 billion times each year, a person walks into a doctor's office, and that person becomes a patient. You or someone you love will be that patient sometime very soon. How will you talk to your doctors? What will they tell you? I have conversations with these patients with rare and deadly diseases. These conversations are terribly fraught16. They're fraught with horrible phrases like I have bad news or there's nothing more we can do. Sometimes these conversations turn on a single word - terminal. Silence can also be rather uncomfortable. Where the blanks are in medicine can be just as important as the words that we use in these conversations. What are the unknowns? What are the experiments that are being done?

I'll never forget the night that I walked into one of my patients' rooms. He was a boy I had diagnosed with a bone cancer a few days before. It was almost midnight when I got to his room. He was asleep. But I found his mother reading by flashlight next to his bed. Turned out that what she had been reading was the protocol17 that the chemotherapy doctors had given her that day. She had memorized it. She said, Dr. Jones, you told me that we don't always win with this type of cancer. But I've been studying this protocol, and I think I can do it. I think I can comply with these very difficult treatments. I'm going to quit my job. I'm going to move in with my parents. I'm going to keep my baby safe.

I didn't tell her. I didn't stop to correct her thinking. She was trusting in a protocol that, even if complied with, wouldn't necessarily save her son. I didn't fill in that blank. But a year and a half later, her boy, nonetheless, died of his cancer. Should I have told her?

(SOUNDBITE OF MUSIC)

RAZ: One of the things you said in another part of your talk, Kevin, is that you see every patient as, like, a new experiment, right? And every time, it's a gamble of if it's going to work or not.

JONES: Yeah. We're going to find out with someone's life and health, and so it counts. It matters. You know, it's interesting because I think we all like stories, right? We like a beginning and a middle and an end. And so scientists are wanting to tell a story. And the challenge is that sometimes the story can carry us away.

And so if we don't have humility, then we will stop honestly inquiring about things. And so that's why I really think that the humility is critical because we have to sort of hold ourselves back. We have to rein18 ourselves in when we are so excited about a story that we can start to see things where they aren't really there.

RAZ: Yeah. Yeah, I mean, we're wired to ask questions, right? Like as Michael Stevens said earlier, you know, like, we sort of emerged from the savannas19 of East Africa out into the wider world because we were curious.

JONES: Yeah. We ask questions, yeah, totally agree. And what's so critical, I think, is asking the correct questions. And really, we cannot really say with science what is going to happen. We can guess and then we can test it and see what happens. So I really think the key is asking the correct questions. What can I do? What can I choose? And can I test that moving forward? I love that about scientific inquiry is that it is intrinsically forward-looking.

(SOUNDBITE OF MUSIC)

RAZ: Dr. Kevin Jones - you can see his full talk at ted.com. On the show today, ideas about The Spirit Of Inquiry. I'm Guy Raz, and you're listening to the TED Radio Hour from NPR.


点击收听单词发音收听单词发音  

1 inquiry nbgzF     
n.打听,询问,调查,查问
参考例句:
  • Many parents have been pressing for an inquiry into the problem.许多家长迫切要求调查这个问题。
  • The field of inquiry has narrowed down to five persons.调查的范围已经缩小到只剩5个人了。
2 uncertainty NlFwK     
n.易变,靠不住,不确知,不确定的事物
参考例句:
  • Her comments will add to the uncertainty of the situation.她的批评将会使局势更加不稳定。
  • After six weeks of uncertainty,the strain was beginning to take its toll.6个星期的忐忑不安后,压力开始产生影响了。
3 ted 9gazhs     
vt.翻晒,撒,撒开
参考例句:
  • The invaders gut ted the village.侵略者把村中财物洗劫一空。
  • She often teds the corn when it's sunny.天好的时候她就翻晒玉米。
4 definitively bfa3c9e3e641847693ee64d5d8ab604b     
adv.决定性地,最后地
参考例句:
  • None of the three super-states could be definitively conquered even by the other two in combination. 三个超级国家中的任何一国都不可能被任何两国的联盟所绝对打败。 来自英汉文学
  • Therefore, nothing can ever be definitively proved with a photograph. 因此,没有什么可以明确了一张照片。 来自互联网
5 humility 8d6zX     
n.谦逊,谦恭
参考例句:
  • Humility often gains more than pride.谦逊往往比骄傲收益更多。
  • His voice was still soft and filled with specious humility.他的声音还是那么温和,甚至有点谦卑。
6 humble ddjzU     
adj.谦卑的,恭顺的;地位低下的;v.降低,贬低
参考例句:
  • In my humble opinion,he will win the election.依我拙见,他将在选举中获胜。
  • Defeat and failure make people humble.挫折与失败会使人谦卑。
7 albeit axiz0     
conj.即使;纵使;虽然
参考例句:
  • Albeit fictional,she seemed to have resolved the problem.虽然是虚构的,但是在她看来好象是解决了问题。
  • Albeit he has failed twice,he is not discouraged.虽然失败了两次,但他并没有气馁。
8 humbly humbly     
adv. 恭顺地,谦卑地
参考例句:
  • We humbly beg Your Majesty to show mercy. 我们恳请陛下发发慈悲。
  • "You must be right, Sir,'said John humbly. “你一定是对的,先生,”约翰恭顺地说道。
9 remains 1kMzTy     
n.剩余物,残留物;遗体,遗迹
参考例句:
  • He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
  • The remains of the meal were fed to the dog.残羹剩饭喂狗了。
10 tumor fKxzm     
n.(肿)瘤,肿块(英)tumour
参考例句:
  • He was died of a malignant tumor.他死于恶性肿瘤。
  • The surgeons irradiated the tumor.外科医生用X射线照射那个肿瘤。
11 celebrated iwLzpz     
adj.有名的,声誉卓著的
参考例句:
  • He was soon one of the most celebrated young painters in England.不久他就成了英格兰最负盛名的年轻画家之一。
  • The celebrated violinist was mobbed by the audience.观众团团围住了这位著名的小提琴演奏家。
12 champagne iwBzh3     
n.香槟酒;微黄色
参考例句:
  • There were two glasses of champagne on the tray.托盘里有两杯香槟酒。
  • They sat there swilling champagne.他们坐在那里大喝香槟酒。
13 mentor s78z0     
n.指导者,良师益友;v.指导
参考例句:
  • He fed on the great ideas of his mentor.他以他导师的伟大思想为支撑。
  • He had mentored scores of younger doctors.他指导过许多更年轻的医生。
14 standing 2hCzgo     
n.持续,地位;adj.永久的,不动的,直立的,不流动的
参考例句:
  • After the earthquake only a few houses were left standing.地震过后只有几幢房屋还立着。
  • They're standing out against any change in the law.他们坚决反对对法律做任何修改。
15 bluffing bluffing     
n. 威吓,唬人 动词bluff的现在分词形式
参考例句:
  • I don't think he'll shoot—I think he's just bluffing. 我认为他不会开枪—我想他不过是在吓唬人。
  • He says he'll win the race, but he's only bluffing. 他说他会赢得这场比赛,事实上只是在吹牛。
16 fraught gfpzp     
adj.充满…的,伴有(危险等)的;忧虑的
参考例句:
  • The coming months will be fraught with fateful decisions.未来数月将充满重大的决定。
  • There's no need to look so fraught!用不着那么愁眉苦脸的!
17 protocol nRQxG     
n.议定书,草约,会谈记录,外交礼节
参考例句:
  • We must observe the correct protocol.我们必须遵守应有的礼仪。
  • The statesmen signed a protocol.那些政治家签了议定书。
18 rein xVsxs     
n.疆绳,统治,支配;vt.以僵绳控制,统治
参考例句:
  • The horse answered to the slightest pull on the rein.只要缰绳轻轻一拉,马就作出反应。
  • He never drew rein for a moment till he reached the river.他一刻不停地一直跑到河边。
19 savannas 8e6e2e0a16919eb825681014ced032b7     
n.(美国东南部的)无树平原( savanna的名词复数 );(亚)热带的稀树大草原
参考例句:
  • Therefore the jungles and the savannas know of no juvenile delinquency! 因此,丛林和荒原里没有“少年犯罪。” 来自辞典例句
  • My soul flits away into the virgin forests and to the savannas. 我的灵魂飞向森林中的处女地和广漠的平原。 来自互联网
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