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Day and night existed long before the first primitive1 cells coming into being. And that light/dark cycle left its mark on nearly every living thing, microbes, plants, insects, mammals---we all experience circadian rhythms, due to molecular2 clocks in our cells. But that internal timer affects more than just bedtime. The body's cells may actually divide by the clock, too, in fruit flies at least. Researchers gave fruit flies a form of an inflammatory bowel3 disease. In response, the flies' intestinal4 stem cells got busy reparing the gut5, most of them dividing in sync around dawn. But when researchers blocked the action of two clock genes6 in the intestine7, the flies couldn't patch up the damage. Instead of a correlative repair, the cells stalled in various stages of division, indicating that the internal clock plays a role in healing too. Those results appear in the journal Cell Reports. The researchers say the circadian clock might inform healing in us too, since it's such an ancient trait. If so, they say, doctors might want to time surgeries or chemotherapy for when the body is primed to heal, helping8 patients clock a faster recovery.
1 primitive | |
adj.原始的;简单的;n.原(始)人,原始事物 | |
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2 molecular | |
adj.分子的;克分子的 | |
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3 bowel | |
n.肠(尤指人肠);内部,深处 | |
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4 intestinal | |
adj.肠的;肠壁;肠道细菌 | |
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5 gut | |
n.[pl.]胆量;内脏;adj.本能的;vt.取出内脏 | |
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6 genes | |
n.基因( gene的名词复数 ) | |
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7 intestine | |
adj.内部的;国内的;n.肠 | |
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8 helping | |
n.食物的一份&adj.帮助人的,辅助的 | |
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