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(单词翻译:双击或拖选)
In this case, the study addressed a tricky1 problem. For decades, many scientists have said, and many members of the public have believed, that what people eat — the composition of the diet — determines how likely they are to get a chronic2 disease. But that has been hard to prove. Studies of dietary fiber3 and colon4 cancer failed to find that fiber was protective, and studies of vitamins thought to protect against cancer failed to show an effect.
Many cancer researchers have questioned large parts of the diet-cancer hypothesis, but it has kept a hold on the public imagination. "Nothing fascinates the American public so much as the notion that what you eat rather than how much you eat affects your health," said Dr. Libby, the Harvard professor.
The study found that women who were randomly5 assigned to follow a low-fat diet ate significantly less fat over the next eight years. But they had just as much breast and colon cancer and just as much heart disease. The women were not trying to lose weight, and their weights remained fairly steady. But their experiences with the diets allowed researchers to question some popular notions about diet and obesity6.
There is a common belief that Americans get fat because they eat too many carbohydrates7. The idea is that a high-carbohydrate, low-fat diet leads to weight gain, higher insulin and blood glucose8 levels, and more diabetes9, even if the calories are the same as in a higher-fat diet. That did not happen here.
Others have said the opposite: that low-fat diets enable people to lose weight naturally. But that belief was not supported by this study.
As for heart disease risk factors, the only one affected10 was LDL cholesterol11, which increases heart disease risk. The levels were slightly higher in women eating the higher-fat diet, but not high enough to make a noticeable difference in their risk of heart disease.
Although all the study participants were women, the colon cancer and heart disease results should also apply to men, said Dr. Jacques Rossouw, the project officer for the Women's Health Initiative.
Dr. Rossouw said the observational studies that led to the hypothesis about colon cancer and dietary fat included men and women. With heart disease, he said, researchers have found that women and men respond in the same way to dietary fat.
The most recent study follows a smaller one, reported last year, on low-fat diets for women who had breast cancer. That study hinted that eating less fat might help prevent a recurrence12. But the current study, asking if a low-fat diet could protect women from breast cancer in the first place, had findings that fell short of statistical13 significance, meaning they could have occurred by chance.
Dr. Rossouw said he was still intrigued14 by the breast cancer data, even though it was not statistically15 significant. The women on low-fat diets had a 9 percent lower rate of breast cancer; the incidence was 42 per thousand per year in women in the low-fat diet group, compared with 45 per thousand per year in women consuming their regular diet.
1 tricky | |
adj.狡猾的,奸诈的;(工作等)棘手的,微妙的 | |
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2 chronic | |
adj.(疾病)长期未愈的,慢性的;极坏的 | |
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3 fiber | |
n.纤维,纤维质 | |
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4 colon | |
n.冒号,结肠,直肠 | |
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5 randomly | |
adv.随便地,未加计划地 | |
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6 obesity | |
n.肥胖,肥大 | |
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7 carbohydrates | |
n.碳水化合物,糖类( carbohydrate的名词复数 );淀粉质或糖类食物 | |
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8 glucose | |
n.葡萄糖 | |
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9 diabetes | |
n.糖尿病 | |
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10 affected | |
adj.不自然的,假装的 | |
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11 cholesterol | |
n.(U)胆固醇 | |
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12 recurrence | |
n.复发,反复,重现 | |
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13 statistical | |
adj.统计的,统计学的 | |
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14 intrigued | |
adj.好奇的,被迷住了的v.搞阴谋诡计(intrigue的过去式);激起…的兴趣或好奇心;“intrigue”的过去式和过去分词 | |
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15 statistically | |
ad.根据统计数据来看,从统计学的观点来看 | |
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