At the Lindau Nobel Laureate meeting in Lindau Germany, this will just take a little time than a usual minute.
Edmond Fischer won the Nobel Prize in Physiology or Medicine in 1992 for his discoveries with Edwin Krebs about the way protein get activated, and cellular processes get regulated, the simple process called phosphorylation.
Now 81 years old, Fischer spoke to the students at Lindau Nobel Laureate meeting about the difference between research when he was working in the 1950s and the way he conducts today.
Science was conducted in a total different way, in those days, in facts, since the days of clued beyond that, The French physiologists who first show the glycogenic action of the Pancreas, one observed a physiological phenomenon and then one tried to detect the fact the enzymes, the hormones, responsible for it.
Where as today, by and larger see other way around, first enzymes proteins are discovered and with completions of I don't know how many genome sequencing. Projects hundreds of being discovered, then by over-expressing them, knocking them in and out when tries to determine their function.
So to paraphrase xx, we went from 6 functions in search for an an enzyme to hundreds of enzyme protein, in search of a function.
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