upend 的意思是上下颠倒，掀翻。Opposition politicians in Africa face tough challenges as they struggle to upend decades of rule by the parties that originally brought liberation from colonialism. 非洲的反对派政治人士面临着艰巨的挑战，他们在努力推倒最初将非洲从殖民统治中解放出来的政党数十年的统治。