You are driving me crazy.我快被你搞疯了。

This computer is annoying me.这电脑让我生气。

I'm fed up with the music.我受够这音乐了。

What's wrong?怎么了？

What's the matter?怎么了？

What's up?怎么了？

I‘ve had enough.我真是受够了！

I can't take this anymore.我没办法再忍受了！

I can't stand it anymore.我没办法再忍受了！

Don't take it out on me.可别把气出在我身上.