They discovered that when a famine was able to trigger an effect was different for the grandmother than the grandfather. The grandmother appeared susceptible while she herself was still in the womb, w...
Olov Bygren was looking to see if poor nutrition had an effect on health when he stumbled on something curious. It appeared that a famine could affect people almost 100 years later even if they never...
But could this effect be transmitted to their offspring? They found nearly 200 women of whom a number had actually been in the Twin Towers. About half of them developed post-traumatic stress disorder....
Our studies had really convinced me that it were the later experiences of the child as the child was growing up bombarded with years and years of, em, symptoms from the parents that accounted for the...
The email was sent by Olov Bygren. He was studying the population records of an obscure town in northern Sweden, Overkalix. What made these records unique was their detail. They recorded births and de...
No body had had seen this kind of thing before, so this was the first time and all the people looking at the gel and saying "No, this can't be right and that's the wrong gel ", you know, how you get e...
After we had seen how relatively easy it was to change the switches in mouse embryos, we thought that perhaps the same could be true of human embryos. In IVF, you also have the embryo for a brief peri...
If inheritance was not just about DNA, if these gene switches were so important, just what could turn them on or off? Stephanie and Emend Mullins have two children, Karen and Charlotte. When we were t...
It showed that there was clearly more to inheritance than simply the coded sequence of DNA. We then realized that we were dealing with what is now known as genomic imprinting. What genomic imprinting...
...lead to the end of diseases like cancer... Alzheimer's , Parkinson's , diabetes. The list is endless. We were thinking of genes in a very mechanical way. We were thinking of them just in terms of t...