SCIENCE IN THE NEWS - Gene Map of Malaria / Concerns About G

SCIENCE IN THE NEWS - October 15, 2002 : Gene¹ Map of Malaria² / Concerns About Genetic³ Engineering /
AIDS Warning for Five Countries

VOICE ONE:

This is Bob Doughty⁴.

VOICE TWO:

And this is Steve Ember with Science in the News, a VOA Special English program about recent developments
in science. Today, we tell about a major new discovery about the organisms that cause and spread the disease
malaria. We tell about some concerns about genetic engineering. And we tell about a serious increase in the
disease AIDS in five countries.

((THEME))

VOICE ONE:

Two international teams of scientists have completed a map of the genetic material of the main organism that
causes malaria. They also have mapped the genes⁵ of the mosquito insect that spreads the disease to people.
Experts say this genetic information will speed the development of new drugs to treat or prevent the deadly
disease.

Malaria infects about five-hundred-million people each year. Ninety percent of them are in southern Africa. The
disease kills more than two-and-one-half-million people a year. Most of the victims are children. Doctors say
new drugs and chemicals against malaria are urgently needed. All of the major chemicals and drugs in use are old
and their effectiveness is decreasing.

VOICE TWO:

The latest research appeared in the British publication Nature and the American publication Science. The results
also were announced at news conferences in London and Washington, D.C. More than one-hundred-sixty
scientists from ten countries identified the genetic maps. A number of public and private organizations paid for
the research.

American and British scientists led the effort to complete the genetic map of the Anopheles gambiae (an-OFF-ohleez GAM-bee) mosquito. This insect is sometimes called a “malaria machine.
”
The female mosquito spreads
the most severe kind of malaria. The insect breaks through human skin with its long, tube-like feeding device.
The female mosquito bites people and drinks their blood.

When it bites a person with malaria, the mosquito gets the organism that causes the disease. This organism is a
parasite⁶ called Plasmodium falciparum (plas-MO-dee-um fall-SIP-ah-rum). The parasite invades the mosquito’s
stomach and reproduces. The mosquito then bites other people and spreads the malaria parasite to them.

VOICE ONE:

The scientists collected genetic material from seven-hundred-sixty mosquitoes. A computer program showed that
the mosquito has about fourteen-thousand genes. The researchers found seventy-nine genes that are probably
involved in the mosquito’s sense of smell. They also found seventy-two genes probably involved in its sense of
taste. This information could lead to better chemicals to protect people from mosquito bites.

The researchers also identified which mosquito genes act after the mosquito drinks human blood. Some of these
genes protect the insect. They remove poisons from iron in the blood. The mosquitoes would die if this process
could be blocked.

VOICE TWO:


The researchers also identified the genes in the Plasmodium falciparum parasite. They found that the parasite has
about five-thousand-three-hundred genes. About two-thirds of these genes are not similar to any human genes.
This suggests that chemicals developed to attack the parasite might not harm humans. One such drug has been
proven effective in animals.

The scientists also found the genes the parasite uses to invade red blood cells in humans. Malaria infection might
be prevented if the action of those genes could be blocked. The parasite appears to have more than two-hundred
genes that help it defeat the human body’s defense⁷ system against disease.

VOICE ONE:

Anthony Fauci (FOW-chee) directs the National Institute of Allergy⁸ and Infectious Diseases near Washington, D

C. Doctor Fauci praised the research. He noted⁹ that scientists now have identified the genes of the three
organisms involved in malaria
–
the parasite, the mosquito and the human victim.
A scientist with the World Health Organization said the research is an important development in the history of
science. He said the powers of modern technology are being used against an ancient disease.

((MUSIC BRIDGE))

VOICE TWO:

A new report released by the National Academy of Sciences concerns genetically¹⁰ engineered plants and animals.
The report says the greatest concern is that they may become mixed with wild animal and plant populations. A
committee of the National Research Council wrote the report.

The United States Food and Drug Administration requested the report. That agency is preparing to rule on the
safety of animal and plant products that are developed through genetic engineering.

VOICE ONE:

The report says that genetically changed animals or plants may escape into the wild. Some kinds of animals like
fish, birds and insects can move very quickly. They could easily spread and reproduce faster than wild animals.
This means that wild animals might not be able to compete with genetically engineered ones for food and mates.

The study also says that there are unknown dangers from the substances produced by genetically engineered
animals. Genetically changed animals might produce proteins that cause serious health reactions in some people.
These reactions are called allergies¹¹. A large percentage of people might react severely¹² to some protein produced
through an unknown side-effect of genetic change.

VOICE TWO:

Another issue of concern is the use of products that come from animals genetically engineered to produce nonfood products. For example, a cow that is genetically changed for the qualities of its skin, or leather, should not
be used for food. The committee says it is important to make sure that no food products come from such animals.
This will require official action and new laws.

The committee said the well-being¹³ of genetically changed animals is also a major issue. It found that there are
several effects that scientists should investigate more carefully. For example, studies have found that genetically
changed cows and sheep give birth to baby animals that are much larger than normal. This has caused an increase
in births that require operations instead of natural births.

Genetic engineering sometimes causes major genetic mistakes. The results of these genetic mistakes are animals
with abnormal body parts or changed chemical qualities. The way animals act also can be changed genetically.

Currently, there are few laws governing how to deal with genetically engineered animals and plants. The Food
and Drug Administration has asked the owners of several hundred genetically copied cows to avoid selling them
or permitting them to reproduce. The F-D-A has not yet decided¹⁴ if the cows or their products can safely be sold
or used.


((MUSIC BRIDGE)
)
VOICE ONE:
A new American report warns that rates of infection from the AIDS virus will rise sharply by the year two-

thousand-ten. The National Intelligence Council prepared the report for the United States Central Intelligence
Agency. It says the increase will result mainly from the spread of AIDS in five countries. They are China, India,
Ethiopia, Nigeria and Russia.

The report estimates that the number of people infected in those countries could increase to between fifty-million
and seventy-five-million. That is three times the number currently estimated. It also is far more than the number
of AIDS cases expected in central and southern Africa. That number is expected to increase to as many as thirty-
five-million people.

VOICE TWO:

China, India, Ethiopia, Nigeria and Russia have more than forty percent of the world’s population. Officials
warn that the increase of AIDS could harm the economic, social, political and military systems in these countries.
The report estimates that India might have as many as twenty-five-million AIDS victims by two-thousand-ten.

That is the highest estimate of any country.

The report says the AIDS virus is spreading at different rates in the five countries. It says that risky¹⁵ sexual
activity is increasing infection rates in all five. The problem is reported to be most severe in Nigeria and Ethiopia.
((THEME)
)
VOICE ONE:
This SCIENCE IN THE NEWS program was written by Jerilyn Watson, Mario Ritter and George Grow. It was

produced by George Grow. This is Bob Doughty.
VOICE TWO:
And this is Steve Ember. Join us again next week for more news about

 

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1 gene   

n.遗传因子，基因

参考例句：

• A single gene may have many effects.单一基因可能具有很多种效应。
• The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。

2 malaria   

n.疟疾

参考例句：

• He had frequent attacks of malaria.他常患疟疾。
• Malaria is a kind of serious malady.疟疾是一种严重的疾病。

3 genetic   

adj.遗传的，遗传学的

参考例句：

• It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
• Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。

4 doughty   

adj.勇猛的，坚强的

参考例句：

• Most of successful men have the characteristics of contumacy and doughty.绝大多数成功人士都有共同的特质：脾气倔强，性格刚强。
• The doughty old man battled his illness with fierce determination.坚强的老人用巨大毅力与疾病作斗争。

5 genes   

n.基因( gene的名词复数 )

参考例句：

• You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因，所以能够活得很长。 来自《简明英汉词典》
• Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪

6 parasite   

n.寄生虫；寄生菌；食客

参考例句：

• The lazy man was a parasite on his family.那懒汉是家里的寄生虫。
• I don't want to be a parasite.I must earn my own way in life.我不想做寄生虫，我要自己养活自己。

7 defense   

n.防御，保卫；[pl.]防务工事；辩护，答辩

参考例句：

• The accused has the right to defense.被告人有权获得辩护。
• The war has impacted the area with military and defense workers.战争使那个地区挤满了军队和防御工程人员。

8 allergy   

n.(因食物、药物等而引起的)过敏症

参考例句：

• He developed an allergy to pollen.他对花粉过敏。
• The patient had an allergy to penicillin.该患者对青霉素过敏。

9 noted   

adj.著名的，知名的

参考例句：

• The local hotel is noted for its good table.当地的那家酒店以餐食精美而著称。
• Jim is noted for arriving late for work.吉姆上班迟到出了名。

10 genetically   

adv.遗传上

参考例句：

• All the bees in the colony are genetically related. 同一群体的蜜蜂都有亲缘关系。
• Genetically modified foods have already arrived on American dinner tables. 经基因改造加工过的食物已端上了美国人的餐桌。 来自英汉非文学 - 生命科学 - 基因与食物

11 allergies   

n.[医]过敏症；[口]厌恶，反感；（对食物、花粉、虫咬等的）过敏症( allergy的名词复数 )；变态反应，变应性

参考例句：

• Food allergies can result in an enormous variety of different symptoms. 食物过敏会引发很多不同的症状。 来自辞典例句
• Let us, however, examine one of the most common allergies; hayfever. 现在让我们来看看最常见的变态反应的一种--枯草热。 来自辞典例句

12 severely   

adv.严格地；严厉地；非常恶劣地

参考例句：

• He was severely criticized and removed from his post.他受到了严厉的批评并且被撤了职。
• He is severely put down for his careless work.他因工作上的粗心大意而受到了严厉的批评。

13 well-being   

n.安康，安乐，幸福

参考例句：

• He always has the well-being of the masses at heart.他总是把群众的疾苦挂在心上。
• My concern for their well-being was misunderstood as interference.我关心他们的幸福，却被误解为多管闲事。

14 decided   

adj.决定了的，坚决的；明显的，明确的

参考例句：

• This gave them a decided advantage over their opponents.这使他们比对手具有明显的优势。
• There is a decided difference between British and Chinese way of greeting.英国人和中国人打招呼的方式有很明显的区别。

15 risky   

adj.有风险的，冒险的

参考例句：

• It may be risky but we will chance it anyhow.这可能有危险，但我们无论如何要冒一冒险。
• He is well aware how risky this investment is.他心里对这项投资的风险十分清楚。