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(单词翻译:双击或拖选)
Washington
01 November 2007
A coalition1 of international public health officials says drug-resistant2 tuberculosis3 is a man-made epidemic4 caused by a lack of global response to TB. The officials say more resources are needed to fight what is an otherwise curable disease. VOA's Jessica Berman reports.
The World Health Organization estimates that 1.6 million people die each year of tuberculosis.
The reason there are so many deaths, according to the former U.N. Special Envoy5 for HIV/AIDS in Africa Stephen Lewis, is the failure of public health officials to promptly6 identify and properly treat people who are infected with TB, a situation that has led to multi-drug resistant forms of tuberculosis.
The bacterium7 that causes TB becomes resistant to antibiotics8 when patients fail to complete the entire course of antibiotics, which involves a complicated regimen of antibiotics lasting9 up to six months.
Individuals who are infected with AIDS are particularly vulnerable to TB because of their weakened immune systems. Stephen Lewis says up to 80 percent of people with TB also have AIDS. Data compiled by the World Health Organization show that the largest number of deaths from tuberculosis are in Africa, where AIDS is rampant10.
The global community has committed resources to treat 1.6 million people with tuberculosis by 2015. But Lewis notes there are 420,000 new cases of multi-drug resistant tuberculosis each year.
And, he says, only two percent of these people are receiving adequate treatment.
"You begin to verge11 in the area of crimes against humanity you know, you begin to wonder when governments are inert12 and when the international community is in such obvious default, whether there doesn't come a point where these are almost criminal matters, where people are dying in such numbers that you can absolutely stop it and fail to do so," Lewis said.
Drug-resistant tuberculosis comes in two forms. Multi-drug resistant tuberculosis, or MDR-TB, occurs when the tuberculosis infection is resistant to one or both of the front-line anti-TB drugs, isoniazid and rifampicin.
The other form is called extensively drug-resistant tuberculosis, or XDR-TB, in which the TB bacterium does not respond to any of the older antibiotics and is resistant to at least one of the newer drugs.
Treatment for drug-resistant tuberculosis involves more radical13 treatment. Those with drug-resistant TB who fail to get the treatment can easily spread the disease to others.
Paul Farmer is founder14 of the group Partners in Health. Farmer says it is a misconception that MDR- or XDR-TB cannot be conquered.
"The goal in treatment is to have multiple drugs, at least three or four, and sometimes even surgery," he said. "So, if you have an area of the lung that is affected15, and other parts of the lung that are unaffected, if you have surgical16 capacity removing that part of the lung can increase cure rates."
If various combinations of old and new antibiotics fail, Farmer says surgery can cure drug-resistant tuberculosis in about 50 percent of patients.
Nesri Padayatchi of South Africa's Center for the AIDS Program of Research says it is difficult to get financing for TB tests, clinics, personnel and treatments when no one is paying attention.
"I think everyone is really bored with TB," Padayatchi said. "TB is a very, very, very old disease. And it's really only become very sexy and fashionable because of HIV. And in fact, there should be a lot more attention paid to TB because HIV is strictly17 a behavioral issue and TB is about breathing really. It affects everybody."
The comments on TB come ahead of an international conference on tuberculosis next week in South Africa.
1 coalition | |
n.结合体,同盟,结合,联合 | |
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2 resistant | |
adj.(to)抵抗的,有抵抗力的 | |
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3 tuberculosis | |
n.结核病,肺结核 | |
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4 epidemic | |
n.流行病;盛行;adj.流行性的,流传极广的 | |
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5 envoy | |
n.使节,使者,代表,公使 | |
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6 promptly | |
adv.及时地,敏捷地 | |
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7 bacterium | |
n.(pl.)bacteria 细菌 | |
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8 antibiotics | |
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 ) | |
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9 lasting | |
adj.永久的,永恒的;vbl.持续,维持 | |
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10 rampant | |
adj.(植物)蔓生的;狂暴的,无约束的 | |
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11 verge | |
n.边,边缘;v.接近,濒临 | |
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12 inert | |
adj.无活动能力的,惰性的;迟钝的 | |
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13 radical | |
n.激进份子,原子团,根号;adj.根本的,激进的,彻底的 | |
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14 Founder | |
n.创始者,缔造者 | |
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15 affected | |
adj.不自然的,假装的 | |
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16 surgical | |
adj.外科的,外科医生的,手术上的 | |
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17 strictly | |
adv.严厉地,严格地;严密地 | |
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