VOA标准英语2010年-Iron-Regulating Protein Could Help Bat

Almost all cells need iron to grow. Now, researchers have identified a link between the body's system for regulating iron and breast cancer. The discovery could help doctors predict the course of breast cancer disease and even help them decide the most appropriate treatment.

Iron is a vital nutrient¹, but too much iron can be harmful. Researchers at Wake Forest University in Winston-Salem, North Carolina, looked at a certain protein that regulates iron and studied the amount of it in breast cancer cells.

"And what we found is that a protein called ferroportin that removes iron from cells, that eliminates iron from cells, was markedly reduced in breast cancers when compared to normal breast cells. And in fact was most reduced in the most aggressive breast cancers," said Frank Torti, who led the research team.

They found that ferroportin levels were a good predictor of the course of the cancer, specifically whether breast cancer survivors² would have a recurrence³ of the disease.

"When ferroportin was high, women did well, and when ferroportin was low, women did poorly."

The predictive power of ferroportin is still just a laboratory finding, but Torti says it suggests a possible novel approach to cancer therapy.

"I think that our study points to ferroportin as a target for the development of cancer drugs. In other words, we and others will be looking at ways to raise ferroportin in cancer cells, and that might be an important target for breast cancer treatment and eventually a treatment that can be used in patients."

Wake Forest University professor Frank Torti was interviewed by the journal Science Translational Medicine, which published his findings in their online edition
 

1 nutrient   

adj.营养的，滋养的；n.营养物，营养品

参考例句：

• Magnesium is the nutrient element in plant growth.镁是植物生长的营养要素。
• The roots transmit moisture and nutrient to the trunk and branches.根将水分和养料输送到干和枝。

2 survivors   

幸存者，残存者，生还者( survivor的名词复数 )

参考例句：

• The survivors were adrift in a lifeboat for six days. 幸存者在救生艇上漂流了六天。
• survivors clinging to a raft 紧紧抓住救生筏的幸存者

3 recurrence   

n.复发，反复，重现

参考例句：

• More care in the future will prevent recurrence of the mistake.将来的小心可防止错误的重现。
• He was aware of the possibility of a recurrence of his illness.他知道他的病有可能复发。