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(单词翻译:双击或拖选)
A new study of stroke in the United States has found that the rate of brain-damaging blood clots1 has increased dramatically among people infected with HIV. The increase in strokes coincides with the use of newer, more effective AIDS medicines.
Bruce Ovbiagele of the University of California, San Diego, and his colleagues analyzed2 a database of medical records for the decade starting in 1997.
During that period, hospitalizations for stroke in the U.S. declined by seven percent. "But when you look in the HIV population," Ovbiagele said, "they actually increased almost about 60 percent across the decade. So stroke rates were going up among HIV-infected individuals while they were going down in the general population."
The scientist says the data used in this study is not sufficient to explain definitively3 why strokes increased in people with HIV. But he believes it's not a coincidence that the surge in strokes came just as HIV patients began using more powerful drugs known as highly active antiretroviral therapies, or HAART medications.
"Now we know that HAART medications have metabolic4 complication, which include abnormal changes in cholesterol5, unfavorable changes in cholesterol. We know that they can also cause increased deposition6 of fat within the body. And both these things are risk factors for stroke."
Ovbiagele says his study suggests that HIV-positive individuals and their doctors have to be vigilant7 and proactive to reduce the risk of stroke.
"Screening for high blood pressure should be regular and frequent and treated promptly8," he said in a telephone interview. "Screening for high cholesterol should be regular, frequent, and treated promptly. So these are the kinds of things that clinicians and patients should be vigilant about looking for to try and avert9 a stroke from occurring."
This data was limited to U.S. patients, so he says it's not possible to say if the same pattern of strokes among people with HIV is present in other countries
1 clots | |
n.凝块( clot的名词复数 );血块;蠢人;傻瓜v.凝固( clot的第三人称单数 ) | |
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2 analyzed | |
v.分析( analyze的过去式和过去分词 );分解;解释;对…进行心理分析 | |
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3 definitively | |
adv.决定性地,最后地 | |
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4 metabolic | |
adj.新陈代谢的 | |
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5 cholesterol | |
n.(U)胆固醇 | |
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6 deposition | |
n.免职,罢官;作证;沉淀;沉淀物 | |
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7 vigilant | |
adj.警觉的,警戒的,警惕的 | |
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8 promptly | |
adv.及时地,敏捷地 | |
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9 avert | |
v.防止,避免;转移(目光、注意力等) | |
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