VOA标准英语2011--Malaria Vaccine Shows Acceptable Safety, Efficacy Results

Malaria¹ Vaccine² Shows Acceptable Safety, Efficacy Results

An international health alliance working to develop a vaccine against malaria says one of its most advanced vaccines³, called RTS,S, shows promising⁴ results. After two years of human clinical trials in Africa, the PATH Malaria Vaccine Initiative and its collaborators report the vaccine provides protection against malaria for children aged⁵ five to 17 months.

Scientists working on the world’s first-ever malaria vaccine are calling the RTS,S trials a significant milestone⁶.

“For 40 years people have been trying to develop malaria vaccine and here we are,” said Dr. Christian⁷ Loucq, the director of Malaria Vaccine Initiative, which is an international non-profit group involved in assessing the safety and effectiveness of the new vaccine. Thousands of children in seven countries in Africa received the vaccine. Investigators⁸ found that in vaccinated⁹ children, the risk of severe and clinical malaria was reduced by half.

“Phase Three is where you look into efficacy and safety for which we had consistent results and we are very happy and encouraged to move on,” said Dr. Daniel Ansong, a pediatrician and researcher at one of the clinical-trial sites in Ghana.

Dr. Ansong believes the vaccine will be a valuable new weapon in the global war on malaria.

Critics note that in the field trials, the new vaccine was only 47 percent effective against severe malaria, a level of protection they say should be higher. But pediatricians say that with malaria killing¹⁰ 800,000 children every year, even this level of efficacy could save thousands of lives.

Dr. Joe Cohen is co-inventor of the RTS,S vaccine and a researcher at the drug companty GlaxoSmith-line. It has invested $300 million in malaria vaccine development.

Cohen says developing a vaccine against malaria has been a major scientific challenge. “The problem, I think, is the parasite¹¹ itself. Malaria parasite - parasites¹² in general - very complex organisms, with complex DNA¹³ makeup¹⁴ with many thousands of genes¹⁵, in contrast to bacteria or viruse,” he said.

GlaxoSmith-Kline says it expects to invest an additional $50 to 100 million in the vaccine program. Researchers say they will start testing the vaccine on larger populations after the successful completion of ongoing¹⁶ Phase Three trials.

The developers plan to submit the final results of the vaccine trials to the World Health Organization by 2014. Their hope is that the WHO will recommend that the malaria vaccine become a routine part of all future childhood immunization programs.

1 malaria   

n.疟疾

参考例句：

• He had frequent attacks of malaria.他常患疟疾。
• Malaria is a kind of serious malady.疟疾是一种严重的疾病。

2 vaccine   

n.牛痘苗，疫苗；adj.牛痘的，疫苗的

参考例句：

• The polio vaccine has saved millions of lives.脊髓灰质炎疫苗挽救了数以百万计的生命。
• She takes a vaccine against influenza every fall.她每年秋季接种流感疫苗。

3 vaccines   

疫苗，痘苗( vaccine的名词复数 )

参考例句：

• His team are at the forefront of scientific research into vaccines. 他的小组处于疫苗科研的最前沿。
• The vaccines were kept cool in refrigerators. 疫苗放在冰箱中冷藏。

4 promising   

adj.有希望的，有前途的

参考例句：

• The results of the experiments are very promising.实验的结果充满了希望。
• We're trying to bring along one or two promising young swimmers.我们正设法培养出一两名有前途的年轻游泳选手。

5 aged   

adj.年老的，陈年的

参考例句：

• He had put on weight and aged a little.他胖了，也老点了。
• He is aged,but his memory is still good.他已年老，然而记忆力还好。

6 milestone   

n.里程碑；划时代的事件

参考例句：

• The film proved to be a milestone in the history of cinema.事实证明这部影片是电影史上的一个里程碑。
• I think this is a very important milestone in the relations between our two countries.我认为这是我们两国关系中一个十分重要的里程碑。

7 Christian   

adj.基督教徒的；n.基督教徒

参考例句：

• They always addressed each other by their Christian name.他们总是以教名互相称呼。
• His mother is a sincere Christian.他母亲是个虔诚的基督教徒。

8 investigators   

n.调查者，审查者( investigator的名词复数 )

参考例句：

• This memo could be the smoking gun that investigators have been looking for. 这份备忘录可能是调查人员一直在寻找的证据。
• The team consisted of six investigators and two secretaries. 这个团队由六个调查人员和两个秘书组成。 来自《简明英汉词典》

9 vaccinated   

[医]已接种的，种痘的，接种过疫菌的

参考例句：

• I was vaccinated against tetanus. 我接种了破伤风疫苗。
• Were you vaccinated against smallpox as a child? 你小时候打过天花疫苗吗？

10 killing   

n.巨额利润；突然赚大钱，发大财

参考例句：

• Investors are set to make a killing from the sell-off.投资者准备清仓以便大赚一笔。
• Last week my brother made a killing on Wall Street.上个周我兄弟在华尔街赚了一大笔。

11 parasite   

n.寄生虫；寄生菌；食客

参考例句：

• The lazy man was a parasite on his family.那懒汉是家里的寄生虫。
• I don't want to be a parasite.I must earn my own way in life.我不想做寄生虫，我要自己养活自己。

12 parasites   

寄生物( parasite的名词复数 )； 靠他人为生的人； 诸虫

参考例句：

• These symptoms may be referable to virus infection rather than parasites. 这些症状也许是由病毒感染引起的，而与寄生虫无关。
• Kangaroos harbor a vast range of parasites. 袋鼠身上有各种各样的寄生虫。

13 DNA   

(缩)deoxyribonucleic acid 脱氧核糖核酸

参考例句：

• DNA is stored in the nucleus of a cell.脱氧核糖核酸储存于细胞的细胞核里。
• Gene mutations are alterations in the DNA code.基因突变是指DNA密码的改变。

14 makeup   

n.组织；性格；化装品

参考例句：

• Those who failed the exam take a makeup exam.这次考试不及格的人必须参加补考。
• Do you think her beauty could makeup for her stupidity?你认为她的美丽能弥补她的愚蠢吗？

15 genes   

n.基因( gene的名词复数 )

参考例句：

• You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因，所以能够活得很长。 来自《简明英汉词典》
• Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪

16 ongoing   

adj.进行中的，前进的

参考例句：

• The problem is ongoing.这个问题尚未解决。
• The issues raised in the report relate directly to Age Concern's ongoing work in this area.报告中提出的问题与“关心老人”组织在这方面正在做的工作有直接的关系。