VOA标准英语2012--Untreatable New Forms of TB Raising Alarm

Untreatable New Forms of TB Raising Alarm

The World Health Organization (WHO) lists 69 countries that have reported what is officially called "extensively drug-resistant" tuberculosis¹ (XDR-TB). It's a form of the mycobacterium that, like the one reported in India, isn't killed by first- and second-line anti-TB injectable drugs. The WHO says at least 25,000 cases of XDR-TB are reported worldwide every year.
Dr. Margaret Chan, WHO's director-general, views the emergence² of drug-resistant tuberculosis with alarm.
"Call it what you may, a time bomb or a powder keg. Any way you look at it, this is a potentially explosive situation," she said.
Officials say drug-resistant TB has been a growing problem in countries such as India and China because patients are frequently misdiagnosed and often receive inappropriate or inadequate⁴ treatment with antibiotics⁵. Misuse⁶ of these drugs increases the danger that the target pathogen will gradually develop resistance to them.
Dr. Neeraj Mistry, a public health physician, says surveys show that very few Indian doctors are actually treating TB patients with the right drugs for the right length of time.
"The emergence of totally-resistant TB is a result of failed public health intervention⁷ strategies," said Mistry. "When we deliver ineffective treatment regimens and when we don't have full adherence⁸ and compliance⁹ to treatment, it enables the emergence of resistance within the individual."
Experts say that with the current arsenal¹⁰ of drugs failing to hold the line against TB, the need for new drugs and compounds has become more urgent. Preventing TB through vaccination¹¹ is one promising¹² strategy.
"The ideal would be to develop a vaccine¹³ that works in all age groups. Everyone from newborn through the elderly," noted¹⁴ Dr. Ann Ginsberg of the Aeras Global TB Vaccine Foundation.
Ginsberg and her colleagues are running clinical trials on two TB vaccines¹⁵ they hope will provide long-lasting immunity¹⁶ to TB and stop transmission of the disease. If all goes as planned, she says, the vaccine will be ready by 2020.
"The clinical development program for a TB vaccine is a very long process, and it's long because, first of all, it's the nature of the disease itself - people get infected with TB and often don't get sick for years," added Ginsberg. "So when you do a vaccine trial, you have to vaccinate¹⁷ people and watch them for years to see whether or not they will get the TB. So that makes these clinical trials very long."
While the world waits for that TB vaccine, the WHO says a new line of TB drugs - fortified¹⁸ with a new class of potent³ anti-mycobacterial agents - could be available by the end of this year or early next.

1 tuberculosis   

n.结核病，肺结核

参考例句：

• People used to go to special health spring to recover from tuberculosis.人们常去温泉疗养胜地治疗肺结核。
• Tuberculosis is a curable disease.肺结核是一种可治愈的病。

2 emergence   

n.浮现，显现，出现，（植物）突出体

参考例句：

• The last decade saw the emergence of a dynamic economy.最近10年见证了经济增长的姿态。
• Language emerges and develops with the emergence and development of society.语言是随着社会的产生而产生，随着社会的发展而发展的。

3 potent   

adj.强有力的，有权势的；有效力的

参考例句：

• The medicine had a potent effect on your disease.这药物对你的病疗效很大。
• We must account of his potent influence.我们必须考虑他的强有力的影响。

4 inadequate   

adj.(for,to)不充足的，不适当的

参考例句：

• The supply is inadequate to meet the demand.供不应求。
• She was inadequate to the demands that were made on her.她还无力满足对她提出的各项要求。

5 antibiotics   

n.（用作复数）抗生素；（用作单数）抗生物质的研究；抗生素，抗菌素( antibiotic的名词复数 )

参考例句：

• the discovery of antibiotics in the 20th century 20世纪抗生素的发现
• The doctor gave me a prescription for antibiotics. 医生给我开了抗生素。

6 misuse   

n.误用，滥用；vt.误用，滥用

参考例句：

• It disturbs me profoundly that you so misuse your talents.你如此滥用自己的才能，使我深感不安。
• He was sacked for computer misuse.他因滥用计算机而被解雇了。

7 intervention   

n.介入，干涉，干预

参考例句：

• The government's intervention in this dispute will not help.政府对这场争论的干预不会起作用。
• Many people felt he would be hostile to the idea of foreign intervention.许多人觉得他会反对外来干预。

8 adherence   

n.信奉，依附，坚持，固着

参考例句：

• He was well known for his adherence to the rules.他因遵循这些规定而出名。
• The teacher demanded adherence to the rules.老师要求学生们遵守纪律。

9 compliance   

n.顺从；服从；附和；屈从

参考例句：

• I was surprised by his compliance with these terms.我对他竟然依从了这些条件而感到吃惊。
• She gave up the idea in compliance with his desire.她顺从他的愿望而放弃自己的主意。

10 arsenal   

n.兵工厂，军械库

参考例句：

• Even the workers at the arsenal have got a secret organization.兵工厂工人暗中也有组织。
• We must be the great arsenal of democracy.我们必须成为民主的大军火库。

11 vaccination   

n.接种疫苗，种痘

参考例句：

• Vaccination is a preventive against smallpox.种痘是预防天花的方法。
• Doctors suggest getting a tetanus vaccination every ten years.医生建议每十年注射一次破伤风疫苗。

12 promising   

adj.有希望的，有前途的

参考例句：

• The results of the experiments are very promising.实验的结果充满了希望。
• We're trying to bring along one or two promising young swimmers.我们正设法培养出一两名有前途的年轻游泳选手。

13 vaccine   

n.牛痘苗，疫苗；adj.牛痘的，疫苗的

参考例句：

• The polio vaccine has saved millions of lives.脊髓灰质炎疫苗挽救了数以百万计的生命。
• She takes a vaccine against influenza every fall.她每年秋季接种流感疫苗。

14 noted   

adj.著名的，知名的

参考例句：

• The local hotel is noted for its good table.当地的那家酒店以餐食精美而著称。
• Jim is noted for arriving late for work.吉姆上班迟到出了名。

15 vaccines   

疫苗，痘苗( vaccine的名词复数 )

参考例句：

• His team are at the forefront of scientific research into vaccines. 他的小组处于疫苗科研的最前沿。
• The vaccines were kept cool in refrigerators. 疫苗放在冰箱中冷藏。

16 immunity   

n.优惠；免除；豁免，豁免权

参考例句：

• The law gives public schools immunity from taxation.法律免除公立学校的纳税义务。
• He claims diplomatic immunity to avoid being arrested.他要求外交豁免以便避免被捕。

17 vaccinate   

vt.给…接种疫苗；种牛痘

参考例句：

• Local health officials then can plan the best times to vaccinate people.这样，当地的卫生官员就可以安排最佳时间给人们接种疫苗。
• Doctors vaccinate us so that we do not catch smallpox.医生给我们打预防针使我们不会得天花。

18 fortified   

adj. 加强的

参考例句：

• He fortified himself against the cold with a hot drink. 他喝了一杯热饮御寒。
• The enemy drew back into a few fortified points. 敌人收缩到几个据点里。