VOA标准英语2012--New Alzheimer's Research Raise Hope for Treatment, Cure

New Alzheimer's Research Raise Hope for Treatment, Cure

Scientists working to unravel¹ the mysteries of Alzheimer's disease are excited by two recent studies. Both provide important new insights on how the disease spreads through the brain.
Guy Eakin is vice² president of the American Health Assistance Foundation, which helped to fund one of the breakthrough studies. He says the study found that the progression of Alzheimer's disease depends on the transmission of an abnormal brain protein known as tau.
"Within our brain, one cell can transfer this tau protein to another cell and then that next cell will become diseased and transfer the tau protein to the next cell down the line. And that actually begins to explain how we see Alzheimer's developing," added Eakin.
Eakin says not every research effort leads to a breakthrough, but the accumulated findings from many previous studies of Alzheimer's, using both animal and human subjects, have drawn³ a much clearer picture of how the disease devastates⁴ the brain.
"In Alzheimer's disease, the destruction of tissue occurs in kind of a spiraling fashion and gradually encompasses⁵ the motor skills as well as emotional areas of the brain and other sensory⁶ mechanisms⁷ of the brain and ultimately overwhelms the brain's capacity," added Eakin.
Another important Alzheimer's study by Dr. William Jagust and colleagues at the University of California, Berkeley, finds that people whose daily routines include stimulating⁸ mental activities, such as reading, writing or solving puzzles, develop fewer of the amyloid plaque⁹ deposits in the brain that are the signature of Alzheimer's.
"What we found [is that] the more cognitively¹⁰ active they were, the less amyloid they had in the Brain," said Jagust.
And another recent study shows that those amyloid plaque deposits can start forming in younger adults and not just in the elderly, as researchers had previously¹¹ believed.
Dr. Brian Appleby did not take part in that study, but treats dementia patients at Cleveland Clinic.
"We might be able to do something much earlier in life to prevent the process," said Appleby.
Dr. Francis Collins, the director of the National Institutes of Health (NIH), believes Alzheimer's research is gaining momentum¹², but there is still a long ways to go before the disease is fully¹³ understood.
"We have a beginning of a molecular¹⁴ picture. I don't want to say that we have all the other pieces together," said Collins.
Some of those pieces may be found in the 50 to 80 drug compounds designed to treat Alzheimer's that are now undergoing trials. Scientists are hoping that at least a few of these drugs will help to slow or stop the disease in its tracks, so that a diagnosis¹⁵ of Alzheimer's is no longer a death sentence.

1 unravel   

v.弄清楚（秘密）；拆开，解开，松开

参考例句：

• He was good with his hands and could unravel a knot or untangle yarn that others wouldn't even attempt.他的手很灵巧，其他人甚至都不敢尝试的一些难解的绳结或缠在一起的纱线，他都能解开。
• This is the attitude that led him to unravel a mystery that long puzzled Chinese historians.正是这种态度使他解决了长期以来使中国历史学家们大惑不解的谜。

2 vice   

n.坏事；恶习；[pl.]台钳，老虎钳；adj.副的

参考例句：

• He guarded himself against vice.他避免染上坏习惯。
• They are sunk in the depth of vice.他们堕入了罪恶的深渊。

3 drawn   

v.拖，拉，拔出；adj.憔悴的，紧张的

参考例句：

• All the characters in the story are drawn from life.故事中的所有人物都取材于生活。
• Her gaze was drawn irresistibly to the scene outside.她的目光禁不住被外面的风景所吸引。

4 devastates   

v.彻底破坏( devastate的第三人称单数 )；摧毁；毁灭；在感情上（精神上、财务上等）压垮

参考例句：

• Strip mining devastates whole regions, leaving bare and useless ground. 露天矿产毁坏全部区域，离开赤裸和无用的地面。 来自互联网
• Prostitution is a profession that devastates the lives of young women. 雏妓这个职业是对女孩子极度的摧残。 来自互联网

5 encompasses   

v.围绕( encompass的第三人称单数 )；包围；包含；包括

参考例句：

• The job encompasses a wide range of responsibilities. 这项工作涉及的职责范围很广。
• Its conservation law encompasses both its magnitude and its direction. 它的守恒定律包括大小和方向两方面。 来自辞典例句

6 sensory   

adj.知觉的，感觉的，知觉器官的

参考例句：

• Human powers of sensory discrimination are limited.人类感官分辨能力有限。
• The sensory system may undergo long-term adaptation in alien environments.感觉系统对陌生的环境可能经过长时期才能适应。

7 mechanisms   

n.机械( mechanism的名词复数 )；机械装置；[生物学] 机制；机械作用

参考例句：

• The research will provide direct insight into molecular mechanisms. 这项研究将使人能够直接地了解分子的机理。 来自《简明英汉词典》
• He explained how the two mechanisms worked. 他解释这两台机械装置是如何工作的。 来自《简明英汉词典》

8 stimulating   

adj.有启发性的，能激发人思考的

参考例句：

• shower gel containing plant extracts that have a stimulating effect on the skin 含有对皮肤有益的植物精华的沐浴凝胶
• This is a drug for stimulating nerves. 这是一种兴奋剂。

9 plaque   

n.饰板，匾，(医)血小板

参考例句：

• There is a commemorative plaque to the artist in the village hall.村公所里有一块纪念该艺术家的牌匾。
• Some Latin words were engraved on the plaque. 牌匾上刻着些拉丁文。

10 cognitively   

参考例句：

• Cognitively,man,the subject of cognition,must classify and categorize the objects. 从认知学角度来看 ，作为认知主体的人对于认知对象必须进行分类和范畴化。 来自互联网
• Cognitively, reference can be studied along with information processing of human mind. 从认知的角度看，要研究人类思维的信息处理过程。 来自互联网

11 previously   

adv.以前，先前（地）

参考例句：

• The bicycle tyre blew out at a previously damaged point.自行车胎在以前损坏过的地方又爆开了。
• Let me digress for a moment and explain what had happened previously.让我岔开一会儿，解释原先发生了什么。

12 momentum   

n.动力，冲力，势头；动量

参考例句：

• We exploit the energy and momentum conservation laws in this way.我们就是这样利用能量和动量守恒定律的。
• The law of momentum conservation could supplant Newton's third law.动量守恒定律可以取代牛顿第三定律。

13 fully   

adv.完全地，全部地，彻底地；充分地

参考例句：

• The doctor asked me to breathe in,then to breathe out fully.医生让我先吸气，然后全部呼出。
• They soon became fully integrated into the local community.他们很快就完全融入了当地人的圈子。

14 molecular   

adj.分子的；克分子的

参考例句：

• The research will provide direct insight into molecular mechanisms.这项研究将使人能够直接地了解分子的机理。
• For the pressure to become zero, molecular bombardment must cease.当压强趋近于零时，分子的碰撞就停止了。

15 diagnosis   

n.诊断，诊断结果，调查分析，判断

参考例句：

• His symptoms gave no obvious pointer to a possible diagnosis.他的症状无法作出明确的诊断。
• The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做一次彻底的调查分析。