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Chinese Scientist Claims First Gene1 Edited Babies
A Chinese scientist claims he successfully created the world’s first genetically-edited babies.
中国一位科学家称,他成功创造出全球首例经过基因编辑的婴儿。
Chinese researcher He Jiankui made the claim in interviews with the Associated Press. He also spoke3 about his research with organizers of an international conference on gene editing in Hong Kong, the AP reported.
中国研究人员贺建奎(He Jiankui)接受美联社采访时发表了上述声明。据美联社报道,他还与香港基因编辑国际会议的组织者提及这份研究。
He is a research professor at China’s Southern University of Science and Technology in the southern city of Shenzhen.
贺建奎是中国南方科技大学的一名研究教授,该校位于南方城市深圳。
He said he had edited the genetic2 substance, or DNA4, of twin girls born a few weeks ago. There was no independent confirmation5 of He’s work and he did not provide written documentation of his research. Many scientists working in genetics say they believe such experimentation6 is dangerous.
他称,他编辑了数周前出生的一对双胞胎女婴的基因物质(DNA)。贺建奎的研究成果目前没有得到独立的证实,他也没有提供有关这项研究的书面文件。很多从事遗传学研究的科学家表示,他们认为这种实验有很高的风险。
He’s claims were immediately condemned7 by some scientists as unsafe and unethical. This kind of gene editing is banned in the United States and many other countries. Such changes to a person’s DNA can pass to future generations and risks harming other genes8.
他的声明立刻招致了一些科学家们的讨伐,称这是不安全和不道德的。这种基因编辑在美国等其它很多国家都被禁止。编辑后的人类基因会遗传给后代,而且有可能损害其它基因。
In interviews, He Jiankui defended his work. He said he had performed the gene editing to help protect the babies from future infection of HIV, the virus responsible for the disease AIDS. He said the process had “worked safely” and the twin girls were “as healthy as any other babies.”
贺建奎在采访中为自己的研究辩护。他说,他进行的这项基因编辑研究,旨在帮助婴儿免受艾滋病毒(HIV)的感染。艾滋病毒会导致艾滋病(AIDS)。他说,这一过程“十分安全”,这对双胞胎女婴“跟其他婴儿一样健康。”
He told the AP he felt a strong responsibility “not just to make a first, but also to make an example” for future research. “Society will decide what to do next,” he said.
贺建奎告诉美联社,他觉得有责任“开创历史先河,并且为未来的研究树立榜样。”他说:“社会将决定下一步的发展方向。”
China to investigate He’s activity
中国对编辑基因研究展开
He had studied in the past at Rice and Stanford universities in the United States. He then returned to his homeland China to open a laboratory at Southern University of Science and Technology.
贺建奎曾在美国赖斯大学以及斯坦福大学深造。之后,他回到了祖国,并在中国南方科技大学创建了一处实验室。
When He’s claims became public, the university issued a statement saying his work had “seriously violated academic ethics9 and standards.” University officials said they had no knowledge of his research and had launched an investigation10. A university spokesman said the professor had been on a break from teaching since early this year. But he remains11 an employee and still works in the laboratory.
当贺建奎的声明公开后,中国南方科技大学发表声明称,他的研究“严重违反了学术伦理规范。”校方官员声称,对这一研究不知情,并已经对此展开调查。校方一位发言人表示,自年初以来,该教授一直暂停教学。但他仍然是该大学的员工,仍然在该实验室工作。
China’s National Health Commission said it was “highly concerned” about the claims and ordered local health officials “to immediately investigate” He’s activity. “We have to be responsible for the people’s health and will act on this according to the law,” the commission said in a statement.
中国国家卫生健康委员会对此表示高度重视,并责令当地卫生官员立即对贺建奎的研究展开调查。该委员会表示:“我们必须对广大人民的健康负责,并将依法采取行动。”
Limited use of gene-editing
基因编辑的限制
Scientists discovered in recent years a new way to edit genes that make up a person’s DNA throughout the body. The tool, called CRISPR-cas9, makes it possible to change DNA to supply a needed gene or take one away that is causing problems.
近年来,科学家们发现了一种新方法,可以编辑构成人体DNA的基因。这种名为CRISPR-cas9的工具或可以改变DNA来提供所需基因或是抹除某种致病基因。
So far the tool has only been used on adults to treat deadly diseases, and the changes only affected12 that person. Editing sperm13, eggs or embryos14 is different because such changes can be passed down. In the U.S., the process is only permitted for lab research. China bans human cloning, but not specifically gene editing.
目前,该工具仅限于治疗成年人的致命疾病,并且这种改变只会影响本人。而编辑精子、卵子或是胚胎则另当别论,因为这种改变会遗传。在美国,该过程仅限于进行实验室研究。中国虽然禁止人类克隆,但是并未具体针对基因编辑。
Kiran Musunuru is a University of Pennsylvania gene editing expert and editor of a genetics journal. He told the Associated Press that if such an experiment had been carried out on human beings, it could not be “morally or ethically15 defensible.”
基兰(Kiran Musunuru)是宾夕法尼亚大学的基因编辑专家,也是遗传学杂志的编辑。他对美联社表示,如果这类实验在人类身上进行,就不可能在“道德和伦理上”站得住脚。
Julian Savulescu, a medical ethics expert at Britain’s University of Oxford16, agreed. “If true, this experiment is monstrous,” he told Reuters.
牛津大学医学伦理专家朱利安(Julian Savulescu)对此表示认同。他说:“如果这是真的,那这个实验太可怕了。”
However, one well-known geneticist, Harvard University’s George Church, defended the attempt to edit genes to prevent infections of HIV. He told the AP that since HIV is “a major and growing public health threat” he finds such experiments “justifiable17.”
然而,哈佛大学一位著名的遗传学专家乔治(George Church)对编辑基因防止艾滋病感染的意图进行了辩护。他告诉美联社,鉴于艾滋病毒是“一种日益严重的重大公共卫生威胁,”他认为这种实验是“合理的。”
Words in This Story
unethical – adj.morally bad
standard – n.level of quality considered acceptable
sperm – n.male reproductive fluid
clone – v.an exact copy of a plant or animal made by scientists removing one of its cells
justifiable – adj.having a good reason
1 gene | |
n.遗传因子,基因 | |
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2 genetic | |
adj.遗传的,遗传学的 | |
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3 spoke | |
n.(车轮的)辐条;轮辐;破坏某人的计划;阻挠某人的行动 v.讲,谈(speak的过去式);说;演说;从某种观点来说 | |
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4 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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5 confirmation | |
n.证实,确认,批准 | |
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6 experimentation | |
n.实验,试验,实验法 | |
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7 condemned | |
adj. 被责难的, 被宣告有罪的 动词condemn的过去式和过去分词 | |
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8 genes | |
n.基因( gene的名词复数 ) | |
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9 ethics | |
n.伦理学;伦理观,道德标准 | |
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10 investigation | |
n.调查,调查研究 | |
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11 remains | |
n.剩余物,残留物;遗体,遗迹 | |
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12 affected | |
adj.不自然的,假装的 | |
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13 sperm | |
n.精子,精液 | |
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14 embryos | |
n.晶胚;胚,胚胎( embryo的名词复数 ) | |
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15 ethically | |
adv.在伦理上,道德上 | |
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16 Oxford | |
n.牛津(英国城市) | |
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17 justifiable | |
adj.有理由的,无可非议的 | |
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