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VOA健康报道2023--Weight Loss Drugs May Risk Complications under Anesthesia

时间:2023-08-29 00:53:31

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Weight Loss Drugs May Risk Complications under Anesthesia

Doctors who practice anesthesiology in the United States and Canada are expressing concern about patients who take popular weight loss drugs leading up to surgery.

Anesthesiologists work together with surgeons to make sure their patients are asleep, or sedated1, before medical procedures.

More and more people are taking the weight loss drugs Ozempic and Wegovy. Anesthesiologists say they are having trouble deciding when surgeries should take place.

That is because the weight loss drugs cause people to hold food in their stomachs longer than usual.

People who still have food in their stomachs when they are put to sleep before surgery risk a complication known as a pulmonary aspiration2. That is that is the term for when someone breathes some of their stomach contents into their lungs. In extreme cases, the food particles can cause infection or even death.

Most patients are told to not eat for about eight hours before surgery. However, the doctors say those guidelines may need to be changed for patients who are using the weight loss drugs.

Ion Hobai is an anesthesiologist at Massachusetts General Hospital in Boston. He said everyone who takes the drugs should know about "such a serious sort of potential complication."

Komodo Health is a technology company that works in healthcare. According to its research, nearly 6 million prescriptions4 for the weight loss drugs were written in the first five months of 2023.

In June, the American Society of Anesthesiologists said patients should not take daily weight loss medications on the day of surgery. It also advised that patients should not get their weekly weight loss injection for a week before any sedation procedures.

Dr. Michael Champeau is the head of the organization. He said the recommendation is based on experiences from anesthesiologists around the United States.

A group of anesthesiologists, including Hobai, said they would recommend even more time off from the drugs before surgery. In the Canadian Journal of Anesthesia, they suggested about three weeks.

Dr. Philip Jones is an anesthesiologist at the Mayo Clinic in Minnesota. After three weeks, he said, the drug should no longer be affecting the stomach. At that point, he said, "everything should go back to normal."

Hobai said he is finishing a study of 200 patients who were using drugs such as Ozempic and Wegovy before surgery. He said his results are similar to a smaller study in Brazil that found 25 percent of patients still had food in their stomachs 10 days after stopping the drug.

Because of this information, the American Society of Anesthesiologists said doctors who are unsure of their patients' stomach contents should work differently. They say doctors should work as they would if they knew the patient's stomach was full.

Aspiration only happens one time out of every 2,000 to 3,000 operations that require sedation. But when it does happen, the patients develop a lung injury half the time. That is why the doctors are concerned.

One of Hobai's patients who had been taking Wegovy developed a problem that required serious care. He had not eaten for 18 hours before surgery.

In another case, a woman taking a small amount of Ozempic did not eat for 10 hours before surgery. She was in the middle of a procedure that had to be stopped because doctors saw food in her stomach.

Dr. Elisa Lund is an anesthesiologist at the University of North Carolina in Chapel5 Hill. She said many doctors have similar stories, as the weight loss drugs have become more common.

"It has exponentially increased," she said.

Novo Nordisk is the drug company that makes Wegovy and Ozempic. The company said there was nothing in its testing that showed the drug would lead to aspiration. However, the drug-maker did say the medications can cause the stomach to empty more slowly.

Hobai said he is also concerned about patients going off their medications for too long. For example, the drugs are used to control the blood sugar level of patients with diabetes6. If they stop taking them before surgery, they may face a different kind of health problem.

He said patients who are using the drugs should tell their doctors about them and discuss the risks of having surgery.

"If you're taking this drug and you need an operation, you will need to have some extra precautions," he said.

Words in This Story

practice –v. to do something again and again, in this case as a task of employment

surgery –n. medical treatment in which a doctor cuts into someone's body in order to repair or remove damaged or diseased parts

procedure –n. a process or way of doing things, in this case related to a medical task done by a doctor

complication –n. a way of speaking about a problem found after a medical procedure such as a surgery

potential –n. the possibility of something happening in the future

prescription3 –n. a written order by a doctor that permits a person to hold and use a medication

exponentially –n. a way of discussing something that grows at a high rate, or higher than usual

precaution –n. taking extra care to prevent a problem


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点击收听单词发音收听单词发音  

1 sedated sedated     
v.使昏昏入睡,使镇静( sedate的过去式和过去分词 )
参考例句:
  • She's sedated,but she's probably scared out of her mind. 她很安静,但是她可能已经吓疯了。 来自电影对白
  • Are you telling me the porn actually sedated you? 你是要告诉我,那毛片的确让你镇静下来吗? 来自电影对白
2 aspiration ON6z4     
n.志向,志趣抱负;渴望;(语)送气音;吸出
参考例句:
  • Man's aspiration should be as lofty as the stars.人的志气应当象天上的星星那么高。
  • Young Addison had a strong aspiration to be an inventor.年幼的爱迪生渴望成为一名发明家。
3 prescription u1vzA     
n.处方,开药;指示,规定
参考例句:
  • The physician made a prescription against sea- sickness for him.医生给他开了个治晕船的药方。
  • The drug is available on prescription only.这种药只能凭处方购买。
4 prescriptions f0b231c0bb45f8e500f32e91ec1ae602     
药( prescription的名词复数 ); 处方; 开处方; 计划
参考例句:
  • The hospital of traditional Chinese medicine installed a computer to fill prescriptions. 中医医院装上了电子计算机来抓药。
  • Her main job was filling the doctor's prescriptions. 她的主要工作就是给大夫开的药方配药。
5 chapel UXNzg     
n.小教堂,殡仪馆
参考例句:
  • The nimble hero,skipped into a chapel that stood near.敏捷的英雄跳进近旁的一座小教堂里。
  • She was on the peak that Sunday afternoon when she played in chapel.那个星期天的下午,她在小教堂的演出,可以说是登峰造极。
6 diabetes uPnzu     
n.糖尿病
参考例句:
  • In case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • Diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。

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