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Possible solution to Kenya's fatal aflatoxin outbreaks
Steve Baragona | Washington, DC 10 June 2010
People sharing and distributing aflasafe on a farm in Nigeria.
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International Institute of Tropical Agriculture
As Kenya suffers with another outbreak of deadly aflatoxin contamination, scientists say a harmless version of the fungus2 that produces the toxin1 could be a powerful ally in preventing future outbreaks.
Aflatoxin is a natural poison produced by a fungus that grows on maize3, cassava, ground nuts, and other crops. The mold thrives in hot, humid conditions.
At high doses, aflatoxin causes liver damage that can be fatal. A 2004 outbreak in Kenya killed at least 125 people.
This month, the Kenyan government warned that at least one person had died and 2.3 million bags of maize were contaminated with the poison.
Aflatoxin is dangerous even at low doses. It can cause cancer, stunt4 children's growth, and weaken the immune system.
Men distributing aflasafe to farmers in Nigeria.
Giving the good guys a head start
Some of the strains found in Kenya produce especially high levels of aflatoxin. But Peter Cotty, a plant disease expert with the U.S. Department of Agriculture, says there also are naturally occurring strains of the fungus in Kenya that produce no aflatoxin at all.
"They occur already in the villages. They're just at low frequency," he says. "We can use techniques to find these fungi5, and we can release them in a manner that allows them to out-compete these very high toxin-producers."
Cotty and his colleagues help the harmless fungi compete by giving them a head start over the bad guys. They grow the good guys on grains such as barley6 or sorghum7 that are sterilized8 so they don't sprout9. When farmers spread these grains among their crops, the harmless mold proliferates10, feeding on dead plants and insects. It will "multiply and spread throughout the field and displace the toxin producers," he says.
Fighting fungus with fungus
Cotty and colleagues at the Nigeria-based International Institute of Tropical Agriculture (IITA) have registered a product called Aflasafe with Nigerian regulators. In field tests last year, farmers who used the grains coated with harmless fungi reduced aflatoxin contamination by an average of 80 percent.
U.S. farmers are also fighting fungus with fungus. For example, cotton growers need to ward11 off aflatoxin contamination or they won't be able to sell the seeds for animal feed. Michael Braverman at Rutgers University manages a program helping12 scientists register new natural crop protection products with U.S. regulators. He says cotton growers in the southwestern state of Arizona use the same method being tested in Nigeria.
"It's effective enough that the growers in Arizona have built their own facility to manufacture this product," he says. "They are not only consumers of the product, they are the official body that owns the registration13."
Peter Cotty and the IITA are now looking for a partner to bring the technology to farmers in Kenya, where aflatoxin contamination is taking a terrible toll14 on people and the economy.
1 toxin | |
n.毒素,毒质 | |
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2 fungus | |
n.真菌,真菌类植物 | |
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3 maize | |
n.玉米 | |
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4 stunt | |
n.惊人表演,绝技,特技;vt.阻碍...发育,妨碍...生长 | |
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5 fungi | |
n.真菌,霉菌 | |
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6 barley | |
n.大麦,大麦粒 | |
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7 sorghum | |
n.高粱属的植物,高粱糖浆,甜得发腻的东西 | |
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8 sterilized | |
v.消毒( sterilize的过去式和过去分词 );使无菌;使失去生育能力;使绝育 | |
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9 sprout | |
n.芽,萌芽;vt.使发芽,摘去芽;vi.长芽,抽条 | |
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10 proliferates | |
激增( proliferate的名词复数 ); (迅速)繁殖; 增生; 扩散 | |
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11 ward | |
n.守卫,监护,病房,行政区,由监护人或法院保护的人(尤指儿童);vt.守护,躲开 | |
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12 helping | |
n.食物的一份&adj.帮助人的,辅助的 | |
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13 registration | |
n.登记,注册,挂号 | |
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14 toll | |
n.过路(桥)费;损失,伤亡人数;v.敲(钟) | |
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