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Wind Offers Clue to Curbing1 Malaria2
A team of scientists studying the patterns of malaria infection in rural Kenyan villages noticed that, despite a gradual reduction of malaria cases in the region, “hotspots” persisted.
The blood-sucking mosquitos that transmit the malaria parasite3 to humans breed in water.
So the researchers decided4 to examine the location of those breeding ponds in relation to the most infected villages. Their findings are published this week in Nature Communications.
Co-author David Smith, an epidemiologist with the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland, says a curious pattern emerged.
“In this study what we did is we looked at the locations of aquatic5 habitats and the locations of humans and we were trying to find out if there was some kind of clustering, which there should be and of course there was. But as we looked even closer what we found was that there was an association between the direction of the wind and the location of where people were at risk.”
Smith says while mosquitos aren’t particularly good flyers, their flight pattern is directed by the scent6 of a potential human host.
“We had a hypothesis that since scents7 travel down wind, that the mosquitos were actually tacking8 across the wind until they found one of those odor plumes9 and then tacking upwind until they found it. We should expect to find that places with higher risk were upwind of larval habitat.”
Smith and his research team studied 642 children living in Kenyan villages after the rainy season, when malaria peaks.
Janet Midega is a medical entomologist with the Kenya Medical Research Institute and co-author of the study. She says scientists compared the malaria case data with the proximity10 of stagnant11 water pools. “What we did find was a lot of the pools of water did have immature12 mosquito stages, and so we sampled these pools of water. We sampled these mosquitos and identified them as the mosquito species that is responsible for malaria transmission in the area.”
The study found that the shorter the distance from those larval incubators, the higher the prevalence of malaria.
Smith says factoring wind into the equation makes it possible to target larval pools downwind from malaria hotspots and so control the disease at its source.
“And the philosophy here is just that knowing it better we might be able to predict the distribution of risk a little bit better, or at least understand what mosquitos are doing so that we can do a better job of distributing nets or interventions13.”
Co-author Janet Midega says while plans are already underway to expand the study in Kenya, replicating14 it elsewhere presents an obvious challenge.
“The applicability of the outcome of these results will be extremely dependent on the local conditions and the mosquitos that are common in that local environment so that control measures are tailored for the local epidemiological situation.”
So, Midega says, prevention strategies will depend on where you live, as some 30 to 40 different mosquito species transmit malaria. Almost half the world’s population - about 3.3 billion people - is at risk. In fact, the mosquito-borne parasitic15 disease strikes some 250 million people every year, and results in nearly one million deaths, largely in sub-Saharan Africa.
1 curbing | |
n.边石,边石的材料v.限制,克制,抑制( curb的现在分词 ) | |
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2 malaria | |
n.疟疾 | |
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3 parasite | |
n.寄生虫;寄生菌;食客 | |
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4 decided | |
adj.决定了的,坚决的;明显的,明确的 | |
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5 aquatic | |
adj.水生的,水栖的 | |
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6 scent | |
n.气味,香味,香水,线索,嗅觉;v.嗅,发觉 | |
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7 scents | |
n.香水( scent的名词复数 );气味;(动物的)臭迹;(尤指狗的)嗅觉 | |
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8 tacking | |
(帆船)抢风行驶,定位焊[铆]紧钉 | |
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9 plumes | |
羽毛( plume的名词复数 ); 羽毛饰; 羽毛状物; 升上空中的羽状物 | |
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10 proximity | |
n.接近,邻近 | |
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11 stagnant | |
adj.不流动的,停滞的,不景气的 | |
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12 immature | |
adj.未成熟的,发育未全的,未充分发展的 | |
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13 interventions | |
n.介入,干涉,干预( intervention的名词复数 ) | |
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14 replicating | |
复制( replicate的现在分词 ); 重复; 再造; 再生 | |
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15 parasitic | |
adj.寄生的 | |
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