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By Jessica Berman
Washington
29 November 2006
The well-known scientific journal Science should require more information from authors, especially if their papers are likely to generate a lot of public attention. That's the conclusion of an independent panel that investigated the publication by Science of fraudulent stem cell research. VOA's Jessica Berman reports.
In 2005, the scientific community was outraged4 when it learned of one of the most high profile fraud cases in history: a group of researchers, led by South Korean biomedical scientist Hwang Woo Suk, claimed for the first time to have derived stem cells from the cloned embryos5 of 11 patients.
derived1 model of Alpha, the larger half of the binary2 near-Earth asteroid3 on the cover of Science's November 2006 issue" hspace="2" src="http://www.tingroom.com/upimg/allimg/070510/1105370.jpg" width="145" vspace="2" border="0" />
Radar-derived model of Alpha, larger half of the binary near-Earth asteroid on cover of Nov. 2006 issue
Stem cells can potentially be manipulated to develop into any tissue of the body, and the news suggested that scientists had jumped a major hurdle6 in customizing the growth of new organs to replace diseased ones.
The landmark7 research was published by Science. But there was one problem. Most, if not all, of the embryos turned out to be fake or never existed at all.
"The fraud was so convincing that peer reviewers didn't catch it, that many U.S. scientists who had heard the work described at small meetings in great detail by Hwang and his collaborators and U.S. scientists who had visited that laboratory in South Korea were surprised and even astonished when the work turned out to be fraudulent," said Donald Kennedy, editor in chief of Science.
The magazine assembled an independent assessment8 committee to investigate the fraud.
The reviewers concluded that, with the pre-publication review process the magazine used, it was unlikely Science could have detected the deception9.
The committee said the system Science has used is based on trust, in which editors merely look for flawed experiments and inconsistencies with other related research.
The committee is recommending that the editors of Science add a strong dose of skepticism when reviewing articles, particularly high-profile research, and that includes asking the authors for the source of their information and insisting that they provide complete data.
John Braumann, the chair of the independent assessment committee, says around 10 articles a year are submitted to Science for publication that probably should receive this kind of scrutiny10 but, even with stricter editorial oversight11, he says the system is not perfect.
"We can ask for more detail when necessary," he said. "But none of us think[s] that all fraud can be detected. But we do think it can be deterred12."
Because of the high profile nature of some of the studies, Braumann says some scientists may try to gain personal recognition or financial gain by misrepresenting their work.
"And we're concerned that science continue to be viewed by the public as an enterprise in which truth is paramount," he added.
Science editor Donald Kennedy says the magazine is now creating a screening process for high-profile research papers, including those dealing13 with stem cells and global warming, while it considers whether to adopt other measures.
1 derived | |
vi.起源;由来;衍生;导出v.得到( derive的过去式和过去分词 );(从…中)得到获得;源于;(从…中)提取 | |
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2 binary | |
adj.二,双;二进制的;n.双(体);联星 | |
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3 asteroid | |
n.小行星;海盘车(动物) | |
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4 outraged | |
a.震惊的,义愤填膺的 | |
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5 embryos | |
n.晶胚;胚,胚胎( embryo的名词复数 ) | |
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6 hurdle | |
n.跳栏,栏架;障碍,困难;vi.进行跨栏赛 | |
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7 landmark | |
n.陆标,划时代的事,地界标 | |
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8 assessment | |
n.评价;评估;对财产的估价,被估定的金额 | |
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9 deception | |
n.欺骗,欺诈;骗局,诡计 | |
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10 scrutiny | |
n.详细检查,仔细观察 | |
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11 oversight | |
n.勘漏,失察,疏忽 | |
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12 deterred | |
v.阻止,制止( deter的过去式和过去分词 ) | |
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13 dealing | |
n.经商方法,待人态度 | |
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