美国有线新闻 CNN 世界首例基因编辑婴儿在中国出生 国内外科学家纷纷谴责

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CARL AZUZ, CNN 10 ANCHOR: A passionate¹ debate is taking place worldwide over claims that genetically⁴ edited human children were recently born in China.

I'm Carl Azuz. This is CNN 10.

Here's how the debate got started. A Chinese scientist named He Jiankui, he's an associate professor at a Chinese university, announced earlier this week that a pair of twin girls was born this month after their embryos⁵ were altered to make them resistant⁶ to human immunodeficiency virus or HIV.

Their parents, according to Professor He, volunteered for the experiment. The father is believed to carry HIV.

Professor He also appeared to suggest that a third genetically modified baby is possible that the pregnancy⁷ is in the early stages.

How could this be done?

Professor He claims to have used CRISPR, a genetic³ editing tool, to alter the twins' DNA⁸. Researchers say CRISPR makes it possible to change a particular part of someone's genome, or delete a gene² altogether.

But the idea of a genetically edited child is highly controversial. For one thing, some scientists doubt this even happened. The research hasn't been independently confirmed. For another, American biologist and Nobel Prize recipient⁹ David Baltimore says genetic editing is irresponsible until it's proven to be safe and effective, and it hasn't yet. Baltimore also says genetically modifying someone to be resistant to HIV isn't necessary since there are other treatments available for the disease that attacks the immune system.

A group of Chinese scientists spoke¹⁰ out against the research, suggesting that experimenting on a human is unethically and crazy. And there are concerns about the consequences of gene editing. A scientist who helped invent CRISPR says when you change one thing, something else gets changed too, and it's not known yet what kinds of effects this could have on the Chinese twins.

For his part, the associate professor says he's proud of his alleged¹¹ achievement because the parents had, quote, lost hope for life, but now, the father plans to work hard and take care of his wife and two daughters.