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Gene1-edited Babies Debate Continues
Six months ago, a Chinese scientist was widely criticized for helping2 make the first gene-edited babies.
Now, new information suggests other people may be interested in doing the same kind of work.
William Hurlbut is a bioethicist at Stanford University in the United States. He told The Associated Press (AP) that a fertility center in Dubai, in the United Arab Emirates, wrote to scientist He Jiankui by email. Hurlburt said the center wanted training in gene editing and asked He for information on the process.
The Chinese scientist reportedly had often asked the Stanford doctor for advice.
Hurlburt told the AP that He told him he had heard from scientists from more than one country, and families with inherited health problems. He said that they had messaged support and interest in changing the genes3 of human embryos5. Hurlbut gave the AP an email he said the Dubai clinic sent to He in December.
It shows “what eagerness there is out there for this technology,” Hurlbut said, and the need “for some sort of enforceable governance” of it.
Other researchers have also heard of people wanting to edit embryos. Jennifer Doudna is with the University of California, Berkeley. She is the co-inventor of the CRISPR gene-editing tool that He used in his research.
Doudna said the reports that others want to edit embryos are “entirely credible7.” She said scientists need to work on establishing policies for how and when such work should happen.
She added that the technology is “not ready for clinical use in human embryos.” But, she said, research should continue.
Doudna receives money from the Howard Hughes Medical Institute, which supports the AP’s health and science reporting.
Last November, He reported that he had changed the genes of twin girls when they were embryos. He claimed he did this before the girls were born to help them resist possible infection with the AIDS virus.
International standards for gene-editing
Ever since then, scientists and policy leaders have been debating the need for international standards, or controls. Editing embryos’ genes is illegal in many countries because it risks damaging other genes. The changes in the genes also can be passed to future generations. It is unknown how editing one generation will affect the next. Many scientists condemned8 He’s work.
Some have also criticized researchers who were thought to have known about, or strongly suspected, what He was doing.
Hurlbut and two other employees at Stanford University were cleared of any wrongdoing. Rice University in Texas is still looking into whether He’s former advisor9, Professor Michael Deem, may have been involved.
Hurlbut, said some people have expressed support for He and his research.
“If you call (He) a rogue10 scientist who did this all by himself, you miss the truth,” Hurlbut said, adding, “then you fail to see what’s wrong” with the way science is governed around the world.
The Chinese scientist has not been seen publicly since shortly after he spoke11 at a conference in Hong Kong in November. The AP’s efforts to reach him by telephone and email were unsuccessful.
He’s claim has yet to appear in a scientific publication, but the babies’ existence seems to have been confirmed by investigators12 in Guangdong province. According to China’s official Xinhua news agency, investigators said He avoided supervision13 of his work and violated research norms out of a desire for publicity14.
There has been no information on how the two girls are doing. Information is also lacking on the second pregnancy15 He achieved with a gene-edited embryo4. This one is thought to be about seven months along now.
International committees have been formed to look into how to deal with the issue.
I’m Anne Ball.
And I’m Jill Robbins.
Words in This Story
gene-edited – adj. genes, containing DNA6, that have been changed before being put back in a body
bioethicist – n. a person who studies the ethics16 and implications of certain biological and medical procedures, technologies and treatments
inherited – adj. to have (a characteristic, disease, etc.) because of the genes that you get from your parents when you are born
eagerness – n. very excited and interested
credible – adj. able to be believed : reasonable to trust or believe
rogue – adj. used to describe something or someone that is different from others in usually a dangerous or harmful way
achieve – v. to get or reach (something) by working hard
clinic - n. a place where people get medical help?
twin – n. ?either one of two babies that are born at the same time to the same mother?
according to – prep as stated, reported, or recorded by (someone or something)
1 gene | |
n.遗传因子,基因 | |
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2 helping | |
n.食物的一份&adj.帮助人的,辅助的 | |
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3 genes | |
n.基因( gene的名词复数 ) | |
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4 embryo | |
n.胚胎,萌芽的事物 | |
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5 embryos | |
n.晶胚;胚,胚胎( embryo的名词复数 ) | |
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6 DNA | |
(缩)deoxyribonucleic acid 脱氧核糖核酸 | |
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7 credible | |
adj.可信任的,可靠的 | |
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8 condemned | |
adj. 被责难的, 被宣告有罪的 动词condemn的过去式和过去分词 | |
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9 advisor | |
n.顾问,指导老师,劝告者 | |
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10 rogue | |
n.流氓;v.游手好闲 | |
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11 spoke | |
n.(车轮的)辐条;轮辐;破坏某人的计划;阻挠某人的行动 v.讲,谈(speak的过去式);说;演说;从某种观点来说 | |
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12 investigators | |
n.调查者,审查者( investigator的名词复数 ) | |
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13 supervision | |
n.监督,管理 | |
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14 publicity | |
n.众所周知,闻名;宣传,广告 | |
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15 pregnancy | |
n.怀孕,怀孕期 | |
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16 ethics | |
n.伦理学;伦理观,道德标准 | |
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