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(单词翻译:双击或拖选)
Scientists Race to Contain Malaria1: New Discoveries, More Resistance
Artemisinin has helped cut global malaria deaths by more than 25 percent over the past decade. But now, in parts of Southeast Asia, this drug no longer works. And the World Health Organization's Dr. Shin Young-Soo warns of serious setbacks if drug resistance continues to spread.
"The truth is, that malaria will beat us all unless we do more than what we are doing now, and we do it better," he said.
Controlling malaria involves a range of strategies: using insecticidal bed nets to prevent mosquito bites, spraying insecticides, preventive treatment for children and pregnant women, and controlling or changing mosquitoes, or the malaria parasites3 they carry.
The World Health Organization says that in the last 10 years, 20 countries have brought the disease under control. At a U.S. congressional hearing, Dr. Mark Dybul executive director of the Global Fund to Fight AIDS, Tuberculosis4 and Malaria, said the world is on course to end malaria.
"We've had so much success over the last 10 years that you've heard about, that high-transmission areas are becoming much more confined," said Dybul.
Dybul said global efforts have led to better treatment and more effective control of the mosquito that carries the parasite2.
Dr. Anthony Fauci, at the US National Institutes of Health, points to promising5 research that involves introducing a strain of bacteria into the mosquito.
"It's a bacteria that infects the mosquito, and what it does is it interferes6 with the developmental process that the malaria parasite goes through in the mosquito in its lifecycle," said Fauci.
And once the bacterium7 is in the mosquito, it's passed down to succeeding generations. The hope is, these malaria-proof mosquitoes eventually will replace those that can carry the parasite.
"Which means, if you can get this out there among populations of mosquitoes in different regions of the world in different countries, it could have a profound effect on the control of malaria," said Fauci.
The true test, of course, will come when mosquitos infected with the bacterium are released into the wild. Dr. Guowu Bian is the Michigan State University scientist who led this research. He spoke8 to VOA via Skype.
"I hope in a few years, maybe three or four years, our mosquito can go to the field," he said.
Another promising line of research involves manipulating the mosquito's genes9. Right now, the anopheles mosquito has no defense10 against the malaria parasite. If scientists can change its genetic11 makeup12, the mosquito's immune system could repel13 the organism.
Meanwhile, the clock is ticking as the malaria parasite becomes immune to the world's front-line drug against the disease.
1 malaria | |
n.疟疾 | |
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2 parasite | |
n.寄生虫;寄生菌;食客 | |
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3 parasites | |
寄生物( parasite的名词复数 ); 靠他人为生的人; 诸虫 | |
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4 tuberculosis | |
n.结核病,肺结核 | |
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5 promising | |
adj.有希望的,有前途的 | |
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6 interferes | |
vi. 妨碍,冲突,干涉 | |
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7 bacterium | |
n.(pl.)bacteria 细菌 | |
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8 spoke | |
n.(车轮的)辐条;轮辐;破坏某人的计划;阻挠某人的行动 v.讲,谈(speak的过去式);说;演说;从某种观点来说 | |
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9 genes | |
n.基因( gene的名词复数 ) | |
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10 defense | |
n.防御,保卫;[pl.]防务工事;辩护,答辩 | |
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11 genetic | |
adj.遗传的,遗传学的 | |
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12 makeup | |
n.组织;性格;化装品 | |
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13 repel | |
v.击退,抵制,拒绝,排斥 | |
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