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The big dream for neuroscientists is to be able to watch our brain cells in action, in real time.
Well, new research has maybe found the most promising1 tool yet—a technique to watch individual neurons light up in response to a stimulus2, like flipping3 on a light switch.
Scientists at the Max Planck Institute inserted a light-sensitive protein into a lab mouse. When a neuron fires, calcium4 ions flood through special cell channels. And when this light-sensitive protein binds5 to calcium, it radiates yellow light. So when the neuron fires it glows yellow.
When scientists shot a puff6 of air at the mouse’s whiskers, the brain cells in the sensory7 areas of the cortex glowed yellow. They watch this via thin glass fibers8 inserted into that brain region.
With this technique scientists now have a way to watch single cell activity in many different regions of the brain at once.
The hope is to investigate how the brain forms and loses neural connections during life experiences and when suffering from illnesses such as Alzheimer’s, Parkinson’s and schizophrenia
1 promising | |
adj.有希望的,有前途的 | |
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2 stimulus | |
n.刺激,刺激物,促进因素,引起兴奋的事物 | |
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3 flipping | |
讨厌之极的 | |
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4 calcium | |
n.钙(化学符号Ca) | |
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5 binds | |
v.约束( bind的第三人称单数 );装订;捆绑;(用长布条)缠绕 | |
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6 puff | |
n.一口(气);一阵(风);v.喷气,喘气 | |
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7 sensory | |
adj.知觉的,感觉的,知觉器官的 | |
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8 fibers | |
光纤( fiber的名词复数 ); (织物的)质地; 纤维,纤维物质 | |
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