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 “This year’s prize is about taking the chemical experiment to the cyberspace¹.” Staffan Normark, Permanent Secretary of the Royal Swedish Academy of Sciences at a press conference at 5:45 am US Eastern Time this morning. “The Royal Swedish Academy of Sciences has decided² to award the 2013 Nobel Prize in Chemistry to Professor Martin Karplus at Université de Strasbourg, France and Harvard University, Cambridge, MA, USA., and Professor Michael Levitt at Stanford University, School of Medicine, CA, USA., and Professor Arieh Warshel at University of Southern California, Los Angeles, USA. And the Academy’s XXX for the development of multiscale models for complex chemical systems.” Following the Nobel Prize announcement, Sven Lidin Chairman of this year’s Nobel Committee for the chemistry prize liken the work being honored to see the reaction in a play, “Most chemical methods tell us about what things look like before a reaction and what they look like after reaction. There is a classical picture of this, which is given in many textbooks of chemistry where a chemical reaction is likened to a piece of drama. And if you going to make the measurements before and after, it’s like seeing the actors before Hamlet and all the dead bodies after - then you wonder what happened in the middle. And actually there is some interesting action there. And this is what theoretical chemical provides us with - the whole drama.” Much more about today’s Nobel Prize later today is in the extended Science America podcast Science Talk.