时差N小时 什么是儿童早衰症?(下)

When the lamin A protein is normally made, a chemical piece called farnesyl is lopped off.

当核纤层蛋白A的编码正常时，一种名叫法呢基的化学物质会从细胞核内脱落。

In the progeria cell, the farnesyl stays attached. The mutant protein remains¹ sticky and piles up in the nucleus², altering the cell’s function.

而早衰细胞中的这一化学物质仍然包裹着细胞核。突变后的蛋白质黏着、堆积在细胞核内，改变了细胞的功能。

Progeria research is moving in two complementary directions.

关于儿童早衰症的研究正在向两个互补的方向发展。

Some scientists are working to find treatments for the disease with anti cancer, cholesterol³ lowering, bone strengthening, and immune suppressing drugs.

一些科学家尝试利用抗癌药、降脂药、健骨药、免疫抑制药寻找治疗该疾病的方法。

Others are interested in progeria’s similarity to aging.

另一些科学家则专注于早衰症与自然老化的相似点。

Progeria like changes have been found in unaffected older people’s skin cells.

一些未患早衰症的老年人的皮肤细胞中也出现了类似早衰症的变化。

A protein called prelamin A, which is similar to the mutant protein, increases at low levels and may contribute to hardening of the arteries⁴ and other problems that come with aging.

一种名为前层细胞A的蛋白质与突变后的蛋白质相似，其数量也在缓慢增加，这种蛋白可能会引起动脉硬化及其他老化过程中所出现的问题。

Though progeria is extremely rare, it may in fact hold the key to aging in all individuals.

虽然早衰症极为罕见，但它可能成为所有人衰老的关键线索。

1 remains   

n.剩余物，残留物；遗体，遗迹

参考例句：

• He ate the remains of food hungrily.他狼吞虎咽地吃剩余的食物。
• The remains of the meal were fed to the dog.残羹剩饭喂狗了。

2 nucleus   

n.核，核心，原子核

参考例句：

• These young people formed the nucleus of the club.这些年轻人成了俱乐部的核心。
• These councils would form the nucleus of a future regime.这些委员会将成为一个未来政权的核心。

3 cholesterol   

n.（U）胆固醇

参考例句：

• There is cholesterol in the cell of body.人体细胞里有胆固醇。
• They are determining the serum-protein and cholesterol levels.他们正在测定血清蛋白和胆固醇的浓度。

4 arteries   

n.动脉( artery的名词复数 )；干线，要道

参考例句：

• Even grafting new blood vessels in place of the diseased coronary arteries has been tried. 甚至移植新血管代替不健康的冠状动脉的方法都已经试过。 来自《简明英汉词典》
• This is the place where the three main arteries of West London traffic met. 这就是伦敦西部三条主要交通干线的交汇处。 来自《简明英汉词典》