-
(单词翻译:双击或拖选)
Veggies Help Fight Genetic2 Heart Attack Risk
A new study finds that a diet high in fruits and vegetables can reduce the danger of heart disease among people at highest risk.
Scientists found healthier eating can turn off the risk gene1 and mitigate3 the risk of heart attack.
Researchers studied a large group of more than 27,000 people whose genetic makeup4, or genotype, includes a unique gene associated with an increased risk of heart attack. The scientists wanted to know whether diet could modify this gene variant5, known as 9p21.
Co-author and McMaster University epidemiologist Sonia Anand says they found it could. “Among people with the high risk genotype, their risk of heart attack was about 30 percent increased. However, when they consumed a diet high in raw vegetables and fruits, this risk returned to 1.0 or that of someone who doesn’t have the high risk genotype.”
The research - one of the largest gene-diet interaction studies ever conducted on heart disease - included people from five ethnicities - European, South Asian, Chinese, Latin American and Arab - who were already taking part in heart studies.
The results, published in the journal PloS Medicine, show that a minimum of two servings a day of raw fruits, vegetables and berries seemed to protect people against the adverse6 effects of the bad gene.
Although, Anand says, more is better. “My advice is to consume as many servings of fruits and or vegetables per day as a way to prevent heart disease, especially if you may have a family history of early disease or a genetic risk factor for heart disease.”
Health officials have long recommended this heart-healthy diet to protect against heart disease and other chronic7 diseases like stroke and cancer, but Anand says that only a minority of those people act on it. “Perhaps genetic information will motivate a larger section of society to actually make positive behavior changes.”
The next step in Anand's research is to study the mechanisms8 that trigger or silence the gene-diet interaction. A better understanding of how it works could point the way to new treatments for people with genetic heart attack risk.
1 gene | |
n.遗传因子,基因 | |
参考例句: |
|
|
2 genetic | |
adj.遗传的,遗传学的 | |
参考例句: |
|
|
3 mitigate | |
vt.(使)减轻,(使)缓和 | |
参考例句: |
|
|
4 makeup | |
n.组织;性格;化装品 | |
参考例句: |
|
|
5 variant | |
adj.不同的,变异的;n.变体,异体 | |
参考例句: |
|
|
6 adverse | |
adj.不利的;有害的;敌对的,不友好的 | |
参考例句: |
|
|
7 chronic | |
adj.(疾病)长期未愈的,慢性的;极坏的 | |
参考例句: |
|
|
8 mechanisms | |
n.机械( mechanism的名词复数 );机械装置;[生物学] 机制;机械作用 | |
参考例句: |
|
|