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VOA双语新闻:老年痴呆症症状出现之前的先兆

时间:2011-10-20 07:48来源:互联网 提供网友:木子平儿   字体: [ ]
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  Memory loss and mental confusion are the first overt1 signs of Alzheimer's Disease, an incurable2 and fatal brain ailment3.
记忆力丧失和心智混乱,是老年痴呆症最先出现的症状。这是一种无药可治的脑部致命疾病。
But scientists are starting to find evidence of the disease long before symptoms appear. In the latest research, MRI scans show telltale signs in the brain a decade before memory and thinking are affected4.
但是,科学家们发现了远在这些症状出现之前就开始有的先兆。在最新的一项研究中,核磁共振成像扫描显示出脑部在记忆及思考能力受到影响前10年就已出现的迹象。
The pace of research aimed at understanding and preventing or treating Alzheimer's has been frustratingly5 slow.
为了了解、预防或治疗老年痴呆症的研究步调,缓慢得令人沮丧。
A number of medicines have reached the market in recent years, but at best they only slow the progression of the disease.
近年来有些药物开始上市,但是那些药最多只能延缓这种疾病的发展。
Some researchers think that drugs may be more effective if they're given sooner, before symptoms become apparent.
有些专家认为,如果在出现明显症状之前,及早进行药物治疗,效果可能会好一些。
A researcher at Harvard Medical School, Bradford Dickerson, is exploring an imaging technique that can identify characteristics of the brain that might signal the mental decline to come years later.
哈佛大学医学院的布拉德福德·迪克森正在研究一种成像技术,用来辨识大脑中一种可能预示多年后心智下降的特殊现象。
"So we wanted to test MRI, which is something that we think would potentially be more accessible to people if we end up needing to screen large groups of older subjects for these kinds of changes," Dickerson says.
迪克森说:“我们希望试验核磁共振。我们想,如果今后需要对大量上年纪的人进行筛查,以发现这类改变,很可能就会更多地使用核磁共振成像技术。”
In a new study, Dickerson and his colleagues studied a group of men and women starting when they were in their 70s. At the outset, they were given standard tests, and all of them showed normal memory and mental function. They also got an MRI scan of the brain.
在一项新的研究中,迪克森和他的同事对一群70多岁的人进行检查。首先,他们接受一般性的测验。每个人的记忆力和心智功能都正常。他们同时也接受了脑部核磁共振成像扫描。
Around 10 years later, the participants - now in their 80s - were again tested, and now about one out of four showed symptoms of Alzheimer's.
大约10年后,这些参与研究的老人都已经年逾80。他们再度接受检查。这时,大约每四个人中有一人出现老年痴呆的症状。
Going back to the MRI results from a decade or so earlier, the researchers found differences between the group who still had normal memory and those who were cognitively6 impaired7, differences in Alzheimer's-related parts of the brain.
再回过头来看他们10年前的核磁共振成像扫描,研究人员发现了在记忆力正常和有认知困难的两组人之间的不同。这不同之处出现在大脑中和老年痴呆症有关的部位。
"And it turned out that those areas of the brain were, in subtle ways, smaller in the people who were cognitively normal but over the next eight years or so eventually developed Alzheimer's dementia than the same areas in the brains of people who remained cognitively normal over that period of time."
迪克森说:“结果发现,那些过去有8年时间心智正常、但最后罹患老年痴呆症的人大脑的相关部位,比心智仍旧正常的人,稍微小一点。”
For now, this is just a research finding, but Dickerson sees a time in the not-too-distant future when doctors will tell people of a certain age with no symptoms that it's time to get tested for Alzheimer's.
到目前为止,这只是一项研究中的发现。但是迪克森预见在不久的将来,医生会建议某个年龄段、但还没有老年痴呆症状的病人,提前进行检查。
"I believe that at some point in the next decade or so, we're going to see tests being proposed to be used as screening tools, sort of like colonoscopies are used," Dickerson says. "So that once you get past a certain age, you would undergo this screening test. And I think this MRI method has at least some plausibility8 to be one of those kinds of screening tools."
迪克森说:“我相信在今后10年,我们会看到医生建议做这种检查,就像今天的直肠镜检查一样。一旦到了某个年纪,就得接受筛查。我认为,核磁共振成像扫描至少可能称为筛查的手段之一。”
And the hope is that drugs in use now or yet to be developed will make a significant difference when taken before memory and mental function begin to decline.
未来的希望是,现有的或者研发中的药物,将在病人的记忆力和心智功能开始下降之前服用,从而产生不同的效果。


点击收听单词发音收听单词发音  

1 overt iKoxp     
adj.公开的,明显的,公然的
参考例句:
  • His opponent's intention is quite overt.他的对手的意图很明显。
  • We should learn to fight with enemy in an overt and covert way.我们应学会同敌人做公开和隐蔽的斗争。
2 incurable incurable     
adj.不能医治的,不能矫正的,无救的;n.不治的病人,无救的人
参考例句:
  • All three babies were born with an incurable heart condition.三个婴儿都有不可治瘉的先天性心脏病。
  • He has an incurable and widespread nepotism.他们有不可救药的,到处蔓延的裙带主义。
3 ailment IV8zf     
n.疾病,小病
参考例句:
  • I don't have even the slightest ailment.我什么毛病也没有。
  • He got timely treatment for his ailment.他的病得到了及时治疗。
4 affected TzUzg0     
adj.不自然的,假装的
参考例句:
  • She showed an affected interest in our subject.她假装对我们的课题感到兴趣。
  • His manners are affected.他的态度不自然。
5 frustratingly 488aa946c1ef065e56fbb91da99571e0     
参考例句:
  • Some programs set this limit too close, resulting in frustratingly temperamental scroll behavior. 一些程序将这种限制设置得太窄,导致滚屏的行为变幻无常,令人沮丧。 来自About Face 3交互设计精髓
  • But the process is frustratingly slow. 但这过程慢得让人郁闷。 来自互联网
6 cognitively d28af4705de1f9218cb8ba1d5bdf8372     
参考例句:
  • Cognitively,man,the subject of cognition,must classify and categorize the objects. 从认知学角度来看 ,作为认知主体的人对于认知对象必须进行分类和范畴化。 来自互联网
  • Cognitively, reference can be studied along with information processing of human mind. 从认知的角度看,要研究人类思维的信息处理过程。 来自互联网
7 impaired sqtzdr     
adj.受损的;出毛病的;有(身体或智力)缺陷的v.损害,削弱( impair的过去式和过去分词 )
参考例句:
  • Much reading has impaired his vision. 大量读书损害了他的视力。 来自《现代汉英综合大词典》
  • His hearing is somewhat impaired. 他的听觉已受到一定程度的损害。 来自《现代汉英综合大词典》
8 plausibility 61dc2510cb0f5a78f45d67d5f7172f8f     
n. 似有道理, 能言善辩
参考例句:
  • We can add further plausibility to the above argument. 我们可以在上述论据之外,再进一步增添一个合理的论据。
  • Let us consider the charges she faces, and the legal plausibility of those charges. 让我们考虑一下她面临的指控以及这些指控在法律上的可信性。
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