血液生物标志可预测死亡风险

 　　血液生物标志可预测死亡风险

　　HELSINKI, Feb. 26 (Xinhua) -- A joint¹ medical research conducted by Finnish and Estonian researchers found that some biomarkers in blood sample could predict mortality risk to people who appear healthy, Finnish Broadcasting Company YLE reported on Wednesday.

　　Researchers used NMR Spectroscopy, which is capable to screen large numbers of blood samples in a cost-effective way, to screen blood samples taken from a total of 17,000 Finnish and Estonian people, and measured 106 biomarkers to check if any of them were associated with risks of death.

　　A biomarker is a biological molecule² found in blood, body fluids or tissues that may signal an abnormal process, a condition or a disease. The level of a particular biomarker may indicate a patient's risk of disease, or likely response to a treatment.

　　As a result, the researchers found that those people with elevated levels of four biomarkers plasma³ albumin, alpha-1-acid glycoprotein, very-low-density lipoprotein particle size and citrate in their blood samples had a significantly increased risk of death in the next five years.

　　During the follow-up study, among the participants, 288 persons with a biomarker score in the top 20 percent were dead of life threatening illness, such as heart disease and cancer within five years, while only 15 people in the bottom 20 percent died in the same period.

　　"We believe that in the future these measures can be used to identify people who appear healthy but in fact have serious underlying⁴ illnesses and guide them to proper treatment," said Dr. Johannes Kettunen, a researcher from the University of Helsinki.

　　However, he added that more studies are needed before these findings are implemented⁵ in clinical practice.

　　The research was carried out by researchers from the Institute for Molecular⁶ Medicine Finland, the Finnish National Institute for Health and Welfare, the University of Helsinki, the University of Oulu, the University of Eastern Finland and the Estonian Biobank.

　　The result of the research was published on latest issue of the PLOS Medicine journal.

1 joint   

adj.联合的，共同的；n.关节，接合处；v.连接，贴合

参考例句：

• I had a bad fall,which put my shoulder out of joint.我重重地摔了一跤，肩膀脫臼了。
• We wrote a letter in joint names.我们联名写了封信。

2 molecule   

n.分子，克分子

参考例句：

• A molecule of water is made up of two atoms of hygrogen and one atom of oxygen.一个水分子是由P妈̬f婘̬ 妈̬成的。
• This gives us the structural formula of the molecule.这种方式给出了分子的结构式。

3 plasma   

n.血浆，细胞质，乳清

参考例句：

• Keep some blood plasma back for the serious cases.留一些血浆给重病号。
• The plasma is the liquid portion of blood that is free of cells .血浆是血液的液体部分，不包含各种细胞。

4 underlying   

adj.在下面的，含蓄的，潜在的

参考例句：

• The underlying theme of the novel is very serious.小说隐含的主题是十分严肃的。
• This word has its underlying meaning.这个单词有它潜在的含义。

5 implemented   

v.实现( implement的过去式和过去分词 )；执行；贯彻；使生效

参考例句：

• This agreement, if not implemented, is a mere scrap of paper. 这个协定如不执行只不过是一纸空文。 来自《现代汉英综合大词典》
• The economy is in danger of collapse unless far-reaching reforms are implemented. 如果不实施影响深远的改革，经济就面临崩溃的危险。 来自辞典例句

6 molecular   

adj.分子的；克分子的

参考例句：

• The research will provide direct insight into molecular mechanisms.这项研究将使人能够直接地了解分子的机理。
• For the pressure to become zero, molecular bombardment must cease.当压强趋近于零时，分子的碰撞就停止了。