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VOA双语新闻:科学家研制治疗辐射病新药

时间:2011-10-18 08:03来源:互联网 提供网友:fei   字体: [ ]
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  The serious radiation leaks at Japan's damaged Fukushima-Daiichi nuclear power plant have reawakened public fears about radiation sickness. But what if there were a drug that could not only protect people from dangerous levels of radiation exposure but also heal those actually exposed to damaging nuclear radiation?
日本核泄漏事件重新唤起民众对辐射疾病的恐惧。如果有一种药物,不但能够保护人类免遭辐射伤害,还能治愈核辐射造成的损伤,那该多好?
Researchers say they are developing such a drug - one that can both prevent and repair human cell damage from all types of radiation exposure.
研究人员说,他们正在研发一种新药,可以防止受到辐射,并可以修复被任何辐射线损坏的人类细胞。
Such a healing medication has the potential to lessen1 panic and fear generated by catastrophic reactor2 accidents. Plant workers trying to make repairs near a crippled reactor's radioactive core might be less fearful if they could take a pill to repair their own radiation-damaged cells.
这种药物可能减轻核反应堆灾难性事故所引起的恐慌。在故障核反应堆附近进行修护的工人,如果能事先服用可以修复他们遭辐射损害的细胞的药物,可能会少一些恐惧。
Ramesh Kumar, the CEO of a U.S. drug research firm called Onconova, says his company has just such a wonder drug in the works.
昂克诺瓦Onconova医药公司执行长雷米什·库玛尔说,他的公司正在进行有关Ex-Rad这种“神药”的研发工作。
The company has been collaborating3 on the drug, called Ex-Rad, with scientists at a U.S. Defense4 Department research laboratory. Kumar says early animal trials have been promising5.
昂克诺瓦公司和美国国防部的科学家合作研发这种药物。库玛尔说,早期动物试验的结果令人兴奋。
“Ex-Rad is a drug which is effective in saving a cell damaged by radiation," he says, "and we have found that it can be given in advance of exposure to radiation up to a day ahead or it can be given up to a day after the exposure to radiation.”
他说:“Ex-Rad能有效修复遭辐射损伤的细胞。它可以在接触辐射前一天服用,或者在遭到辐射的次日服用。”
There are existing antidotes7 for radiation exposure which have been approved by the federal Food and Drug Administration (FDA). Potassium iodide, also known as the radiation pill, prevents the body's absorption of the radioactive iodine8 present in reactor emissions9. For a person poisoned by radioactive isotopes10 such as plutonium and cesium - types of radiation being released from the Fukushima reactors11 - FDA-approved drugs such as Prussian Blue capsules can quickly flush radioactive elements from the body. However, right now there are no drugs specifically for treating radiation sickness itself.
美国食品药物管理局核准过一些治疗辐射伤害的解毒药物。其中碘化钾可以防止人体吸收核反应堆泄出的放射性碘。如果有人受到钸和铯等放射性同位素的辐射,美国食品药物管理局核准的普鲁士蓝胶囊能够迅速将身体内的放射性元素冲洗掉。
The Armed Forces Radiobiology Research Institute has been leading the Pentagon's quest for a more effective antidote6 to radiation sickness, which has a wide range of symptoms.
美军放射生物研究所是国防部研究有效治疗辐射疾病药物的主要机构。
“The symptoms of acute radiation sickness will be just exactly like a terrible flu," says Col. Andrew Huff, a spokesman for the research institute. "The person would have headache. They would feel very tired. They would have little bit of fever. They might have some vomiting12 at higher doses all of this and more but at survivable doses it would come on within 24 to 36 hours."
研究所发言人安德鲁·赫夫说,目前食品药物管理局核准的药物,还不能够治疗同时出现的许多症状。赫夫说:“严重的辐射疾病症状就和严重流感一样。患者会头痛、疲劳、发烧,还可能会呕吐 。还有很多其它症状。在辐射剂量不足以导致死亡情形下,这些症状会在24至36小时之内出现。”
According to Huff, the body loses its platelet and neutrophil supply and people can eventually die of bleeding. He says the Pentagon's search for radiation sickness treatments is intensifying13.
赫夫表示,国防部正在加紧对辐射疾病的研究。
“The other more vexing14 problem, the one that we really have to worry about for larger numbers of people - if there were nuclear terrorism - is how much external ionizing penetrating15 radiation a person would get after a nuclear detonation16."
他说:“另外一个更伤脑筋、也是我们为大批的人所担心的问题是,如果发生了核恐怖活动,一个人受到外来的电离辐射会有多少?”
To combat such a crisis - or to treat people exposed to radiation from a damaged nuclear reactor - the Department of Defense and Onconova have collaborated17 on the development of Ex-Rad.
为了应付这种危机,或者为治疗遭受核反应堆受损后辐射泄漏侵袭的民众,美国国防部和昂克诺瓦医药公司合作研发这种叫作Ex-Rad的药物。
“FDA has devised a development path for drugs like Ex-Rad which involves clinical trials, animal studies, and additional controls for manufacturing and we are in the process of completing these studies," says Kumar, whose company is developing Ex-Rad. "We started this process in 2008 under and FDA's Investigational18 New Drug Exemption19. We have carried out clinical studies in human subjects for safety and we are in the process of continuing to do animal efficacy studies so once all of these studies are completed we can get an approval for specific indication. It could be prophylactic20 use before - or after - exposure. It could be injectable or oral.”
昂克诺瓦公司执行长雷米什·库玛尔说:“食品药物管理局为Ex-Rad一类的药物制订了一套研发途径,包括临床试验、动物试验,以及增加对药品生产的控制。我们正在完成这些试验的过程中。这项研发开始于2008年,我们已经进行了人类安全临床试验,正在继续对动物做疗效研究。 所有这些研究都完成之后,我们会获得特殊核准。Ex-Rad可以在遭受辐射之前或之后使用,注射或口服。”
Kumar says Ex-Rad won't be available for at least another two or three years. In the meantime, government officials warn the public to be cautious about the growing number of claims being made on the Internet for anti-radiation drugs that purport21 to be miracle cures.
库玛尔说,Ex-Rad至少在两、三年内还不会上市。与此同时,政府官员警告民众,不要轻信网路上越来越多有关抗辐射灵丹妙药的广告。


点击收听单词发音收听单词发音  

1 lessen 01gx4     
vt.减少,减轻;缩小
参考例句:
  • Regular exercise can help to lessen the pain.经常运动有助于减轻痛感。
  • They've made great effort to lessen the noise of planes.他们尽力减小飞机的噪音。
2 reactor jTnxL     
n.反应器;反应堆
参考例句:
  • The atomic reactor generates enormous amounts of thermal energy.原子反应堆发出大量的热能。
  • Inside the reactor the large molecules are cracked into smaller molecules.在反应堆里,大分子裂变为小分子。
3 collaborating bd93aed5558c4b146fa553d822f7c432     
合作( collaborate的现在分词 ); 勾结叛国
参考例句:
  • Joe is collaborating on the work with a friend. 乔正与一位朋友合作做那件工作。
  • He was not only learning from but also collaborating with Joseph Thomson. 他不仅是在跟约瑟福?汤姆逊学习,而且也是在和他合作。
4 defense AxbxB     
n.防御,保卫;[pl.]防务工事;辩护,答辩
参考例句:
  • The accused has the right to defense.被告人有权获得辩护。
  • The war has impacted the area with military and defense workers.战争使那个地区挤满了军队和防御工程人员。
5 promising BkQzsk     
adj.有希望的,有前途的
参考例句:
  • The results of the experiments are very promising.实验的结果充满了希望。
  • We're trying to bring along one or two promising young swimmers.我们正设法培养出一两名有前途的年轻游泳选手。
6 antidote 4MZyg     
n.解毒药,解毒剂
参考例句:
  • There is no known antidote for this poison.这种毒药没有解药。
  • Chinese physicians used it as an antidote for snake poison.中医师用它来解蛇毒。
7 antidotes b41113c68d2d3073f3a03516447b4675     
解药( antidote的名词复数 ); 解毒剂; 对抗手段; 除害物
参考例句:
  • Treatment involves giving antidotes that Bind the lead in the tissues. 治疗办法有用解毒剂,它会与组织中的铅结合而把它驱逐出去。
  • With Spleen Qi, heat antidotes, such as cough Runfei effectiveness. 具有补脾益气、清热解毒、润肺止咳等功效。
8 iodine Da6zr     
n.碘,碘酒
参考例句:
  • The doctor painted iodine on the cut.医生在伤口上涂点碘酒。
  • Iodine tends to localize in the thyroid.碘容易集于甲状腺。
9 emissions 1a87f8769eb755734e056efecb5e2da9     
排放物( emission的名词复数 ); 散发物(尤指气体)
参考例句:
  • Most scientists accept that climate change is linked to carbon emissions. 大多数科学家都相信气候变化与排放的含碳气体有关。
  • Dangerous emissions radiate from plutonium. 危险的辐射物从钚放散出来。
10 isotopes 92848c3160703e48dc3b552ac6f54115     
n.同位素;同位素( isotope的名词复数 )
参考例句:
  • the many isotopes of carbon 碳的诸多同位素
  • Tritium is one of the mildest radioactive isotopes. 氚是最和缓的放射性同位素之一。 来自《简明英汉词典》
11 reactors 774794d45796c1ac60b7fda5e55a878b     
起反应的人( reactor的名词复数 ); 反应装置; 原子炉; 核反应堆
参考例句:
  • The TMI nuclear facility has two reactors. 三哩岛核设施有两个反应堆。 来自英汉非文学 - 环境法 - 环境法
  • The earliest production reactors necessarily used normal uranium as fuel. 最早为生产用的反应堆,必须使用普通铀作为燃料。
12 vomiting 7ed7266d85c55ba00ffa41473cf6744f     
参考例句:
  • Symptoms include diarrhoea and vomiting. 症状有腹泻和呕吐。
  • Especially when I feel seasick, I can't stand watching someone else vomiting." 尤其晕船的时候,看不得人家呕。”
13 intensifying 6af105724a108def30288b810d78b276     
v.(使)增强, (使)加剧( intensify的现在分词 );增辉
参考例句:
  • The allies are intensifying their air campaign. 联军部队正加大他们的空战强度。 来自辞典例句
  • The rest of the European powers were in a state of intensifying congestion. 其余的欧洲强国则处于越来越拥挤的状态。 来自英汉非文学 - 历史
14 vexing 9331d950e0681c1f12e634b03fd3428b     
adj.使人烦恼的,使人恼火的v.使烦恼( vex的现在分词 );使苦恼;使生气;详细讨论
参考例句:
  • It is vexing to have to wait a long time for him. 长时间地等他真使人厌烦。 来自《现代英汉综合大词典》
  • Lately a vexing problem had grown infuriatingly worse. 最近发生了一个讨厌的问题,而且严重到令人发指的地步。 来自辞典例句
15 penetrating ImTzZS     
adj.(声音)响亮的,尖锐的adj.(气味)刺激的adj.(思想)敏锐的,有洞察力的
参考例句:
  • He had an extraordinarily penetrating gaze. 他的目光有股异乎寻常的洞察力。
  • He examined the man with a penetrating gaze. 他以锐利的目光仔细观察了那个人。
16 detonation C9zy0     
n.爆炸;巨响
参考例句:
  • A fearful detonation burst forth on the barricade.街垒传来一阵骇人的爆炸声。
  • Within a few hundreds of microseconds,detonation is complete.在几百微秒之内,爆炸便完成了。
17 collaborated c49a4f9c170cb7c268fccb474f5f0d4f     
合作( collaborate的过去式和过去分词 ); 勾结叛国
参考例句:
  • We have collaborated on many projects over the years. 这些年来我们合作搞了许多项目。
  • We have collaborated closely with the university on this project. 我们与大学在这个专案上紧密合作。
18 investigational 40cc1a5fc69842700330f6b02d4dbfbc     
[医]调查研究的
参考例句:
  • Investigational New Drug Application (IND) for the compound. 为化合物的研究中的新药物申请(IND)。
  • He said it representsan investigational H.I. 一位博士说:我们已经向成功迈出了重要的一步。
19 exemption 3muxo     
n.豁免,免税额,免除
参考例句:
  • You may be able to apply for exemption from local taxes.你可能符合资格申请免除地方税。
  • These goods are subject to exemption from tax.这些货物可以免税。
20 prophylactic aRLxb     
adj.预防疾病的;n.预防疾病
参考例句:
  • Vaccination and other prophylactic measures can be carried out.可以采取疫苗接种和其他预防措施。
  • The region began to use quinine successfully as a prophylactic.该地区开始成功地用奎宁作为预防剂。
21 purport etRy4     
n.意义,要旨,大要;v.意味著,做为...要旨,要领是...
参考例句:
  • Many theories purport to explain growth in terms of a single cause.许多理论都标榜以单一的原因解释生长。
  • Her letter may purport her forthcoming arrival.她的来信可能意味着她快要到了。
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